Author:Vava, AkhonaDate: 2020DCUN1D1 is an E3 ligase of the neddylation pathway. It mediates the posttranslational modification of majority of the cullin family of proteins with NEDD8. This activity is known to enhance ubiquitination of the cullin RING E3 ligases, however, ...Read more
Author:Apata, OluwagbengaDate:2022There has been significant growth in the use of wind energy as an alternative form of energy by many countries globally. This is in direct response to calls to reduce environmental pollution from the usage of fossil fuels in energy generation. ...Read more
Author:Alheit, BenjaminDate:2022Many natural protective structures, such as alligator armour, turtle shells, and the skulls of many animals including humans, contain networks of sutures; those are, soft tissue that bonds adjacent stiff plates typically made of bone. Such ...Read more
Author:Aboalgasm, HamidaDate:2022Background: Diabetes mellitus with uncontrolled hyperglycaemia is a major cause of cardiovascular complications and mortality. The developing foetal heart in-utero is particularly susceptible to hyperglycaemia through pathological remodelling, ...Read more
Author:Ibrahim, AbdulmuminDate:2022Successful prevention of mother-to-child HIV transmission (PMTCT) programs have reduced the risk of infant HIV infection in South Africa from 8% in 2008 to an estimated 1.4% in 2015, resulting in an increasing population of HIV-exposed ...Read more
Author:Asfaw, Semeneh AyalewDate:2022This is a study about the Ethiopian revolution through the social and cultural developments that formed the Ethiopian capital, Addis Ababa. The largest participants in the social protests of 1974 were predominantly young Addis Ababans with a ...Read more
Author:Hsieh, Jennifer Hsin-WenDate:2022Background Methamphetamine induced psychosis (MAP) and schizophrenia present with similar positive symptoms of psychosis, are characterized by evidence of attentional impairment, and show symptomatic response to treatment with dopamine ...Read more
Author:Kaplan, BentleyDate:2013With its unparalleled growth and distribution, the human species is increasingly conflicting with wildlife over crops, livestock and even human life as it infringes on natural habitat. In the Cape Peninsula, South Africa, urbanisation has ...Read more
Author:Conradie, David GideonDate:2019Paravalvular regurgitation (PVR), which frequently occurs after transcatheter aortic valve replacements (TAVR) can lead to adverse clinical consequences and has been shown to correlate to an increased late mortality and morbidity. Quantification, ...Read more
Author:Rogers, Graeme JDate:2013Ocular trauma is common in low-income countries. Groote Schuur Hospital manages large numbers of patients with the manifestations of ocular trauma every year. The lens and its supporting structures, major refractive components of the eye, may ...Read more
Author:Madonsela, ZiningiDate:2013Wastewater treatment plants represent a source of nutrients for microbial growth and product formation. In an approach in which bioresource productivity is maximised, it is desirable to not only achieve water treatment to the desired standard, ...Read more
Author:Fortuin, Rowan VictorDate: 2022The Southern African Development Community sees high levels of migration. Many children within these groups are undocumented and have no means to prove their identities. This greatly increases their risks of statelessness, which opens the way ...Read more
Author:May, Haydn LiamDate:2014This thesis investigates a hypothetical large scale renewable energy system for South Africa over the long term future using 2050 as a nominal year of analysis. Simulation modeling was used to assess the integration of three renewable energy ...Read more
Author:Mugisha, RonnieDate:2014The LTE-A (Long Term Evolution Advanced) technology constitutes a significant step in the evolution of 3G systems towards 4G. The performance targets set out for L TE Advanced make it an ideal solution to take care of the ever-increasing ...Read more
Author:Loftie-Eaton, MeganDate:2014A key issue in species conservation is a knowledge of the geographic ranges of species, and how these are changing through time. For birds there is a special opportunity to undertake studies of range changes, making use of the data collected ...Read more
Author:Thawer, Sumaiyya GDate:2014Immunity to nematode infections requires a host T helper 2 (Th2) response promoted by epithelial cell driven IL-33 induction of cytokine secretion of Interleukin (IL)-4, 5 and 13 by a range of immune cells including innate lymphoid cells type ...Read more
Author:Thawer, Sumaiyya GDate:2014Immunity to nematode infections requires a host T helper 2 (Th2) response promoted by epithelial cell driven IL-33 induction of cytokine secretion of Interleukin (IL)-4, 5 and 13 by a range of immune cells including innate lymphoid cells type ...Read more
Author:Oyeniran, Kehinde AdewoleDate:2022Maize streak virus (MSV; Genus: Mastrevirus; Family: Geminiviridae) causes maize streak disease (MSD); a major biotic threat to maize farming especially in sub-Saharan Africa, and it neighbouring Indian and Atlantic Ocean Islands, where its ...Read more
Author:Kleemann, BrittaDate:2013The use of photomedicine in ancient civilizations dates back 4000 years ago but it wasn't until the beginning of the 20th century that photodynamic therapy was discovered by man. The “trinity” of photodynamic therapy (PDT) comprises a ...Read more
Author:Li, Yiqun TonyDate:2013The medical success of platinum-based compounds such as cisplatin and its analogues laid the foundation for the synthesis and application of new transition metal complexes in the field of medicine. With the discovery of additional transition ...Read more