Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5

Simple item page
dc.contributor.advisorFlanagan, Colleenen_ZA
dc.contributor.advisorKatz, Ariehen_ZA
dc.contributor.authorFolefoc, Asongna Theresia Forkemen_ZA
dc.date.accessioned2014-07-28T14:54:55Z
dc.date.available2014-07-28T14:54:55Z
dc.date.issued2007en_ZA
dc.descriptionIncludes bibliographical references (p. 100-119).
dc.description.abstractFour mutations of the CCR5 receptor have been identified in the South African population, but the effects of these mutations on CCR5 function and HIV infection are unknown. We have used in vitro methods to assess the ffect of the mutations, Asp2Val, Leu107Phe, Arg225Gln and Arg225stop, on CCR5 interactions with chemokine ligands and HIV.en_ZA
dc.identifier.apacitationFolefoc, A. T. F. (2007). <i>Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry. Retrieved from http://hdl.handle.net/11427/3128en_ZA
dc.identifier.chicagocitationFolefoc, Asongna Theresia Forkem. <i>"Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2007. http://hdl.handle.net/11427/3128en_ZA
dc.identifier.citationFolefoc, A. 2007. Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Folefoc, Asongna Theresia Forkem AB - Four mutations of the CCR5 receptor have been identified in the South African population, but the effects of these mutations on CCR5 function and HIV infection are unknown. We have used in vitro methods to assess the ffect of the mutations, Asp2Val, Leu107Phe, Arg225Gln and Arg225stop, on CCR5 interactions with chemokine ligands and HIV. DA - 2007 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2007 T1 - Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 TI - Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 UR - http://hdl.handle.net/11427/3128 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3128
dc.identifier.vancouvercitationFolefoc ATF. Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2007 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3128en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Medical Biochemistryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedical Biochemistryen_ZA
dc.titleFunctional consequences of South African mutations of the HIV-1 co-receptor, CCR5en_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
thesis_hsf_2007_folefoc_a_t_f.pdf
Size:
11.99 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
PhD / Doctoral