Social trauma and the mu-opioid system in depression

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dc.contributor.advisorThomas, Kevinen_ZA
dc.contributor.advisorSolms, Marken_ZA
dc.contributor.authorMalcolm-Smith, Susanen_ZA
dc.date.accessioned2015-01-03T05:39:34Z
dc.date.available2015-01-03T05:39:34Z
dc.date.issued2011en_ZA
dc.description.abstractThe overarching thesis under investigation is that the endogenous opioid system plays a key role in depression subsequent to traumatic childhood social experiences. This is suggested by the fact that animal work indicates that mu-opioids robustly mediate separation-distress, and that early social stressors lead to long term dysregulation in key related circuitries and neuroanatomical structures.en_ZA
dc.identifier.apacitationMalcolm-Smith, S. (2011). <i>Social trauma and the mu-opioid system in depression</i>. (Thesis). University of Cape Town ,Faculty of Humanities ,Department of Psychology. Retrieved from http://hdl.handle.net/11427/11123en_ZA
dc.identifier.chicagocitationMalcolm-Smith, Susan. <i>"Social trauma and the mu-opioid system in depression."</i> Thesis., University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2011. http://hdl.handle.net/11427/11123en_ZA
dc.identifier.citationMalcolm-Smith, S. 2011. Social trauma and the mu-opioid system in depression. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Malcolm-Smith, Susan AB - The overarching thesis under investigation is that the endogenous opioid system plays a key role in depression subsequent to traumatic childhood social experiences. This is suggested by the fact that animal work indicates that mu-opioids robustly mediate separation-distress, and that early social stressors lead to long term dysregulation in key related circuitries and neuroanatomical structures. DA - 2011 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Social trauma and the mu-opioid system in depression TI - Social trauma and the mu-opioid system in depression UR - http://hdl.handle.net/11427/11123 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/11123
dc.identifier.vancouvercitationMalcolm-Smith S. Social trauma and the mu-opioid system in depression. [Thesis]. University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2011 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/11123en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Psychologyen_ZA
dc.publisher.facultyFaculty of Humanitiesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPsychologyen_ZA
dc.titleSocial trauma and the mu-opioid system in depressionen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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