Insulin, added to nuclei, stimulates transcription of specific genes

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dc.contributor.advisorVon Holt, Clausen_ZA
dc.contributor.authorStickells, Brenda Janeen_ZA
dc.date.accessioned2016-09-28T19:05:29Z
dc.date.available2016-09-28T19:05:29Z
dc.date.issued1990en_ZA
dc.descriptionBibliography: pages 133-155.en_ZA
dc.description.abstractInsulin regulates cellular gene expression and modulates specific mRNA levels in liver cells. As yet, the mechanism of this control is still unclear. The effects are initiated following the binding of insulin to the plasma membrane receptor. Although several mediators of the signal from the plasma membrane to the nucleus have been proposed, none has proved capable of eliciting all of the effects of insulin on gene expression. Therefore, the possibility that insulin itself may directly regulate transcription at the level of the nucleus, was investigated.en_ZA
dc.identifier.apacitationStickells, B. J. (1990). <i>Insulin, added to nuclei, stimulates transcription of specific genes</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/21984en_ZA
dc.identifier.chicagocitationStickells, Brenda Jane. <i>"Insulin, added to nuclei, stimulates transcription of specific genes."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 1990. http://hdl.handle.net/11427/21984en_ZA
dc.identifier.citationStickells, B. 1990. Insulin, added to nuclei, stimulates transcription of specific genes. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Stickells, Brenda Jane AB - Insulin regulates cellular gene expression and modulates specific mRNA levels in liver cells. As yet, the mechanism of this control is still unclear. The effects are initiated following the binding of insulin to the plasma membrane receptor. Although several mediators of the signal from the plasma membrane to the nucleus have been proposed, none has proved capable of eliciting all of the effects of insulin on gene expression. Therefore, the possibility that insulin itself may directly regulate transcription at the level of the nucleus, was investigated. DA - 1990 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1990 T1 - Insulin, added to nuclei, stimulates transcription of specific genes TI - Insulin, added to nuclei, stimulates transcription of specific genes UR - http://hdl.handle.net/11427/21984 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/21984
dc.identifier.vancouvercitationStickells BJ. Insulin, added to nuclei, stimulates transcription of specific genes. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 1990 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/21984en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Molecular and Cell Biologyen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherGenetic transcriptionen_ZA
dc.subject.otherInsulinen_ZA
dc.titleInsulin, added to nuclei, stimulates transcription of specific genesen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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