Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children

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dc.contributor.advisorZar, Heatheren_ZA
dc.contributor.authorPitcher, Richard Den_ZA
dc.date.accessioned2016-07-14T12:23:02Z
dc.date.available2016-07-14T12:23:02Z
dc.date.issued2016en_ZA
dc.description.abstractIntroduction: There are limited data on the chest X-ray (CXR) abnormalities in human immunodeficiency virus (HIV)-infected children in low- and middle-income countries (LMIC's). Aim: To investigate the evolution of CXR abnormalities in HIV-infected children in LMIC's, to correlate this with the severity of HIV-disease, and to assess the impact of anti-retroviral therapy (ART). Method: A prospective longitudinal study evaluating clinical, immunological and radiographic parameters at regular intervals over a minimum of 24 months. CXR abnormalities were stratified by severity and deemed persistent if present for 6 consecutive months or longer. Univariate and multiple logistic regression analyses assessed associations between radiological and clinical/immunological parameters at enrolment. An ordinal multiple logistic regression model assessed the association of enrolment and time-dependent variables with CXR findings over time.en_ZA
dc.identifier.apacitationPitcher, R. D. (2016). <i>Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. Retrieved from http://hdl.handle.net/11427/20351en_ZA
dc.identifier.chicagocitationPitcher, Richard D. <i>"Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2016. http://hdl.handle.net/11427/20351en_ZA
dc.identifier.citationPitcher, R. 2016. Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Pitcher, Richard D AB - Introduction: There are limited data on the chest X-ray (CXR) abnormalities in human immunodeficiency virus (HIV)-infected children in low- and middle-income countries (LMIC's). Aim: To investigate the evolution of CXR abnormalities in HIV-infected children in LMIC's, to correlate this with the severity of HIV-disease, and to assess the impact of anti-retroviral therapy (ART). Method: A prospective longitudinal study evaluating clinical, immunological and radiographic parameters at regular intervals over a minimum of 24 months. CXR abnormalities were stratified by severity and deemed persistent if present for 6 consecutive months or longer. Univariate and multiple logistic regression analyses assessed associations between radiological and clinical/immunological parameters at enrolment. An ordinal multiple logistic regression model assessed the association of enrolment and time-dependent variables with CXR findings over time. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children TI - Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children UR - http://hdl.handle.net/11427/20351 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/20351
dc.identifier.vancouvercitationPitcher RD. Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/20351en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Paediatrics and Child Healthen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPaediatrics and Child Healthen_ZA
dc.titleRadiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected childrenen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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