Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field

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dc.contributor.advisorComrie, Craigen_ZA
dc.contributor.advisorConradie, Lowryen_ZA
dc.contributor.advisorPineda-Vargas, Carlos Aen_ZA
dc.contributor.authorEisa, Mohamed Eltayeb Men_ZA
dc.date.accessioned2014-08-13T20:05:30Z
dc.date.available2014-08-13T20:05:30Z
dc.date.issued2005en_ZA
dc.descriptionIncludes bibliographical references (leaves 181-197).en_ZA
dc.description.abstractWith the aim of improving the reliability and stability of the beams delivered to the nuclear microprobe at IThemba LABS, as well as optimization of the beam characteristics along the Van de Graaf acceleratore beamlines in general, relevant modifications were implemented. The design and layout of the beamlines in general, relevant modifications were implemented. The design and layout of the beamlines were revised. The beam-optical characteristics through the accelerator, from the ion source up to the analysing magnet directly after the accelerator, were calculated and the design optimised, using the computer codes TRANSPORT, IGUN and TOSCA. The ion source characteristics and optimal operating conditions were determined on an ion source test bench. The measured optimal emittance for 90% of the beam intensity was bout 50π mm mrad for an extraction voltage of 6kV. These changes allow operation of the Nuclear Microprobe at proton energies in the range 1 MeV to 4 meV with beam intensities of tens of a pA at the target surface. The capabilities of the nuclear micropobe facility were evaluated in the improved beamline, with particular emphasis to the characertisation of hard human calcium-rich tissue materials. The process of demineralization in teeth erosion due to exposure to acidic media was investigated in a group of test and control healthy human molar teeth. Samples were cut in cubes ofen_ZA
dc.identifier.apacitationEisa, M. E. M. (2005). <i>Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Physics. Retrieved from http://hdl.handle.net/11427/6528en_ZA
dc.identifier.chicagocitationEisa, Mohamed Eltayeb M. <i>"Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Physics, 2005. http://hdl.handle.net/11427/6528en_ZA
dc.identifier.citationEisa, M. 2005. Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Eisa, Mohamed Eltayeb M AB - With the aim of improving the reliability and stability of the beams delivered to the nuclear microprobe at IThemba LABS, as well as optimization of the beam characteristics along the Van de Graaf acceleratore beamlines in general, relevant modifications were implemented. The design and layout of the beamlines in general, relevant modifications were implemented. The design and layout of the beamlines were revised. The beam-optical characteristics through the accelerator, from the ion source up to the analysing magnet directly after the accelerator, were calculated and the design optimised, using the computer codes TRANSPORT, IGUN and TOSCA. The ion source characteristics and optimal operating conditions were determined on an ion source test bench. The measured optimal emittance for 90% of the beam intensity was bout 50π mm mrad for an extraction voltage of 6kV. These changes allow operation of the Nuclear Microprobe at proton energies in the range 1 MeV to 4 meV with beam intensities of tens of a pA at the target surface. The capabilities of the nuclear micropobe facility were evaluated in the improved beamline, with particular emphasis to the characertisation of hard human calcium-rich tissue materials. The process of demineralization in teeth erosion due to exposure to acidic media was investigated in a group of test and control healthy human molar teeth. Samples were cut in cubes of DA - 2005 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field TI - Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field UR - http://hdl.handle.net/11427/6528 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/6528
dc.identifier.vancouvercitationEisa MEM. Optimisation of accelerator optics and the application of nuclear microscopy to the biomedical field. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Physics, 2005 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/6528en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Physicsen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPhysicsen_ZA
dc.titleOptimisation of accelerator optics and the application of nuclear microscopy to the biomedical fielden_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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