The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis

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dc.contributor.advisorJacobs, Muazzamen_ZA
dc.contributor.authorKeeton, Roanne Shayen_ZA
dc.date.accessioned2015-01-10T06:47:52Z
dc.date.available2015-01-10T06:47:52Z
dc.date.issued2009en_ZA
dc.descriptionIncludes abstract.en_ZA
dc.descriptionIncludes bibliographical references (leaves 85-97).en_ZA
dc.description.abstractTumor necrosis factor alpha (TNFα) is critical for host protective immunity against Mycobacterium tuberculosis infection. TNFRp55 and TNFRp75 can both bind TNFα and conduct signaling, however the respective roles, in particular that of TNFRp75 in an M. tuberculosis aerosol inhalation infection was poorly defined. In this study the role of signaling through TNFRp55 and TNFRp75 was investigated using TNFR deficient mice in an aerosol inhalation M. tuberculosis infection model.en_ZA
dc.identifier.apacitationKeeton, R. S. (2009). <i>The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Immunology. Retrieved from http://hdl.handle.net/11427/11889en_ZA
dc.identifier.chicagocitationKeeton, Roanne Shay. <i>"The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Immunology, 2009. http://hdl.handle.net/11427/11889en_ZA
dc.identifier.citationKeeton, R. 2009. The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Keeton, Roanne Shay AB - Tumor necrosis factor alpha (TNF&#945;) is critical for host protective immunity against Mycobacterium tuberculosis infection. TNFRp55 and TNFRp75 can both bind TNF&#945; and conduct signaling, however the respective roles, in particular that of TNFRp75 in an M. tuberculosis aerosol inhalation infection was poorly defined. In this study the role of signaling through TNFRp55 and TNFRp75 was investigated using TNFR deficient mice in an aerosol inhalation M. tuberculosis infection model. DA - 2009 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2009 T1 - The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis TI - The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis UR - http://hdl.handle.net/11427/11889 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/11889
dc.identifier.vancouvercitationKeeton RS. The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Immunology, 2009 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/11889en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Immunologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherImmunologyen_ZA
dc.titleThe role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosisen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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