Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites

dc.contributor.advisorSeoighe, Cathalen_ZA
dc.contributor.authorNgandu, Nobubelo Kwaneleen_ZA
dc.date.accessioned2014-07-28T14:50:32Z
dc.date.available2014-07-28T14:50:32Z
dc.date.issued2009en_ZA
dc.descriptionIncludes abstract.
dc.descriptionIncludes bibliographical references (p. 136-165).
dc.description.abstractThis thesis exposes previously ignored evolutionary characteristics of the synonymous sites of virus nucleotide sequences and contributes new findings to the understanding of the evolution of HIV-1 in relation to the human immune response.en_ZA
dc.identifier.apacitationNgandu, N. K. (2009). <i>Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/3072en_ZA
dc.identifier.chicagocitationNgandu, Nobubelo Kwanele. <i>"Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2009. http://hdl.handle.net/11427/3072en_ZA
dc.identifier.citationNgandu, N. 2009. Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Ngandu, Nobubelo Kwanele AB - This thesis exposes previously ignored evolutionary characteristics of the synonymous sites of virus nucleotide sequences and contributes new findings to the understanding of the evolution of HIV-1 in relation to the human immune response. DA - 2009 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2009 T1 - Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites TI - Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites UR - http://hdl.handle.net/11427/3072 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3072
dc.identifier.vancouvercitationNgandu NK. Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2009 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3072en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Molecular and Cell Biologyen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherCell Biologyen_ZA
dc.titleEvolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sitesen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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