Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques

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dc.contributor.advisorJackson, Graham Ellisen_ZA
dc.contributor.advisorVenter, Gerharden_ZA
dc.contributor.authorMunyuki, Gadzikanoen_ZA
dc.date.accessioned2014-08-13T14:27:33Z
dc.date.available2014-08-13T14:27:33Z
dc.date.issued2012en_ZA
dc.descriptionIncludes abstract.en_ZA
dc.descriptionIncludes bibliographical references.en_ZA
dc.description.abstractThe need to come up with new and novel antibiotics that utilize unique mechanisms, to which bacteria cannot generate resistance, was the main motivation of this study. Tyrocidine peptides are non-selective antibiotics that have such properties. However, very limited information is available about their mechanism of action. The aim of this study was to determine the mechanism of action of tyrocidine peptides, tyrocidine A, tyrocidine B and tyrocidine C.en_ZA
dc.identifier.apacitationMunyuki, G. (2012). <i>Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/6347en_ZA
dc.identifier.chicagocitationMunyuki, Gadzikano. <i>"Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 2012. http://hdl.handle.net/11427/6347en_ZA
dc.identifier.citationMunyuki, G. 2012. Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Munyuki, Gadzikano AB - The need to come up with new and novel antibiotics that utilize unique mechanisms, to which bacteria cannot generate resistance, was the main motivation of this study. Tyrocidine peptides are non-selective antibiotics that have such properties. However, very limited information is available about their mechanism of action. The aim of this study was to determine the mechanism of action of tyrocidine peptides, tyrocidine A, tyrocidine B and tyrocidine C. DA - 2012 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques TI - Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques UR - http://hdl.handle.net/11427/6347 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/6347
dc.identifier.vancouvercitationMunyuki G. Molecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniques. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 2012 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/6347en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Chemistryen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherChemistryen_ZA
dc.titleMolecular mechanism of action of tyrocidine antimicrobial peptides using NMR spectroscopy and computational techniquesen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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