Evidence of ancient papillomavirus recombination

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dc.contributor.authorVarsani, Arvind
dc.contributor.authorvan der Walt, Eric
dc.contributor.authorHeath, Livio
dc.contributor.authorRybicki, Edward P
dc.contributor.authorWilliamson, Anna Lise
dc.contributor.authorMartin, Darren P
dc.date.accessioned2016-07-27T12:47:36Z
dc.date.available2016-07-27T12:47:36Z
dc.date.issued2006
dc.date.updated2016-07-12T16:51:36Z
dc.description.abstractAn open question amongst papillomavirus taxonomists is whether recombination has featured in the evolutionary history of these viruses. Since the onset of the global AIDS epidemic, the question is somewhat less academic, because immune-compromised human immunodeficiency virus patients are often co-infected with extraordinarily diverse mixtures of human papillomavirus (HPV) types. It is expected that these conditions may facilitate the emergence of HPV recombinants, some of which might have novel pathogenic properties. Here, a range of rigorous analyses is applied to full-genome sequences of papillomaviruses to provide convincing statistical and phylogenetic evidence that evolutionarily relevant papillomavirus recombination can occur.en_ZA
dc.identifierhttp://dx.doi.org/10.1099/vir.0.81917-0
dc.identifier.apacitationVarsani, A., van der Walt, E., Heath, L., Rybicki, E. P., Williamson, A. L., & Martin, D. P. (2006). Evidence of ancient papillomavirus recombination. <i>Journal of General Virology</i>, http://hdl.handle.net/11427/20893en_ZA
dc.identifier.chicagocitationVarsani, Arvind, Eric van der Walt, Livio Heath, Edward P Rybicki, Anna Lise Williamson, and Darren P Martin "Evidence of ancient papillomavirus recombination." <i>Journal of General Virology</i> (2006) http://hdl.handle.net/11427/20893en_ZA
dc.identifier.citationVarsani, A., van der Walt, E., Heath, L., Rybicki, E. P., Williamson, A. L., & Martin, D. P. (2006). Evidence of ancient papillomavirus recombination. Journal of general virology, 87(9), 2527-2531.en_ZA
dc.identifier.issn0022-1317en_ZA
dc.identifier.ris TY - Journal Article AU - Varsani, Arvind AU - van der Walt, Eric AU - Heath, Livio AU - Rybicki, Edward P AU - Williamson, Anna Lise AU - Martin, Darren P AB - An open question amongst papillomavirus taxonomists is whether recombination has featured in the evolutionary history of these viruses. Since the onset of the global AIDS epidemic, the question is somewhat less academic, because immune-compromised human immunodeficiency virus patients are often co-infected with extraordinarily diverse mixtures of human papillomavirus (HPV) types. It is expected that these conditions may facilitate the emergence of HPV recombinants, some of which might have novel pathogenic properties. Here, a range of rigorous analyses is applied to full-genome sequences of papillomaviruses to provide convincing statistical and phylogenetic evidence that evolutionarily relevant papillomavirus recombination can occur. DA - 2006 DB - OpenUCT DP - University of Cape Town J1 - Journal of General Virology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2006 SM - 0022-1317 T1 - Evidence of ancient papillomavirus recombination TI - Evidence of ancient papillomavirus recombination UR - http://hdl.handle.net/11427/20893 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/20893
dc.identifier.vancouvercitationVarsani A, van der Walt E, Heath L, Rybicki EP, Williamson AL, Martin DP. Evidence of ancient papillomavirus recombination. Journal of General Virology. 2006; http://hdl.handle.net/11427/20893.en_ZA
dc.languageengen_ZA
dc.publisherMicrobiology Societyen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceJournal of General Virologyen_ZA
dc.source.urihttp://jgv.microbiologyresearch.org/content/journal/jgv
dc.titleEvidence of ancient papillomavirus recombinationen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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