Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury

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dc.contributor.advisorMorrow, Brenda
dc.contributor.authorNourse, Peter
dc.date.accessioned2026-01-20T09:30:54Z
dc.date.available2026-01-20T09:30:54Z
dc.date.issued2025
dc.date.updated2026-01-15T11:01:31Z
dc.description.abstractBackground: Peritoneal dialysis (PD) has long been a mainstay of acute kidney injury (AKI) management in children of all ages, and it remains the most commonly used modality in low-income regions, where continuous kidney replacement therapy (CKRT) is not widely available. Compared to extracorporeal therapies, PD has lower clearance as well as lower and less precise fluid removal. We previously demonstrated increased ultrafiltration and clearances using continuous flow peritoneal dialysis (CFPD) in children with AKI, however the technique described required expensive high-volume CKRT pumps to circulate fluid, as well as high level technical expertise, limiting its utility in resource-constrained settings. Identifying safe, effective and low-cost techniques for CFPD may improve access to dialysis for children with AKI in low-resource settings.
dc.identifier.apacitationNourse, P. (2025). <i>Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. Retrieved from http://hdl.handle.net/11427/42622en_ZA
dc.identifier.chicagocitationNourse, Peter. <i>"Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2025. http://hdl.handle.net/11427/42622en_ZA
dc.identifier.citationNourse, P. 2025. Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury. . University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. http://hdl.handle.net/11427/42622en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Nourse, Peter AB - Background: Peritoneal dialysis (PD) has long been a mainstay of acute kidney injury (AKI) management in children of all ages, and it remains the most commonly used modality in low-income regions, where continuous kidney replacement therapy (CKRT) is not widely available. Compared to extracorporeal therapies, PD has lower clearance as well as lower and less precise fluid removal. We previously demonstrated increased ultrafiltration and clearances using continuous flow peritoneal dialysis (CFPD) in children with AKI, however the technique described required expensive high-volume CKRT pumps to circulate fluid, as well as high level technical expertise, limiting its utility in resource-constrained settings. Identifying safe, effective and low-cost techniques for CFPD may improve access to dialysis for children with AKI in low-resource settings. DA - 2025 DB - OpenUCT DP - University of Cape Town KW - Continuous Flow Peritoneal Dialysis KW - Peritoneal dialysis KW - Acute Kidney Injury KW - Protein removal KW - Glucose absorption KW - Dialysate salt removal KW - Children LK - https://open.uct.ac.za PB - University of Cape Town PY - 2025 T1 - Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury TI - Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury UR - http://hdl.handle.net/11427/42622 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/42622
dc.identifier.vancouvercitationNourse P. Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury. []. University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 2025 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/42622en_ZA
dc.language.isoen
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Paediatrics and Child Health
dc.publisher.facultyFaculty of Health Sciences
dc.publisher.institutionUniversity of Cape Town
dc.subjectContinuous Flow Peritoneal Dialysis
dc.subjectPeritoneal dialysis
dc.subjectAcute Kidney Injury
dc.subjectProtein removal
dc.subjectGlucose absorption
dc.subjectDialysate salt removal
dc.subjectChildren
dc.titleGravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury
dc.typeThesis / Dissertation
dc.type.qualificationlevelDoctoral
dc.type.qualificationlevelPhD
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