Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum

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dc.contributor.advisorWoods, David Ren_ZA
dc.contributor.advisorJones, David Ten_ZA
dc.contributor.authorYoungleson, Jonathan Sinclairen_ZA
dc.date.accessioned2017-01-26T07:34:12Z
dc.date.available2017-01-26T07:34:12Z
dc.date.issued1989en_ZA
dc.date.updated2016-11-22T11:22:14Z
dc.description.abstractClostridium acetobutylicum P262 is an endospore-forming Gram-positive anaerobic bacterium, which has been used for the industrial production of acetone and butanol from carbohydrate substrates. This study forms part of a wider research effort into the genetics and molecular biology of C. acetobutylicum, which has as an ultimate goal the commercial improvement, and a fundamental understanding of the ABE fermentation. The aim of this study was to isolate and characterize genes involved in solventogenesis. The cloning, expression and characterization of the terminal solventogenic butanol dehydrogenase gene ( adhl), and the central pathway β-hydroxybutyryl-CoA dehydrogenase gene (hbd), which form part of a but operon are described.en_ZA
dc.identifier.apacitationYoungleson, J. S. (1989). <i>Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/23245en_ZA
dc.identifier.chicagocitationYoungleson, Jonathan Sinclair. <i>"Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 1989. http://hdl.handle.net/11427/23245en_ZA
dc.identifier.citationYoungleson, J. 1989. Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Youngleson, Jonathan Sinclair AB - Clostridium acetobutylicum P262 is an endospore-forming Gram-positive anaerobic bacterium, which has been used for the industrial production of acetone and butanol from carbohydrate substrates. This study forms part of a wider research effort into the genetics and molecular biology of C. acetobutylicum, which has as an ultimate goal the commercial improvement, and a fundamental understanding of the ABE fermentation. The aim of this study was to isolate and characterize genes involved in solventogenesis. The cloning, expression and characterization of the terminal solventogenic butanol dehydrogenase gene ( adhl), and the central pathway β-hydroxybutyryl-CoA dehydrogenase gene (hbd), which form part of a but operon are described. DA - 1989 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1989 T1 - Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum TI - Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum UR - http://hdl.handle.net/11427/23245 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/23245
dc.identifier.vancouvercitationYoungleson JS. Molecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicum. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 1989 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/23245en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Molecular and Cell Biologyen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMicrobiologyen_ZA
dc.titleMolecular genetic characterization of two solvent pathway dehydrogenases from Clostridium Acetobutylicumen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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