Numerical simulation of implant-bone interaction following cementless joint replacement

dc.contributor.advisorMartin, Johnen_ZA
dc.contributor.advisorSpirakis, Thanosen_ZA
dc.contributor.authorStarke, Gregory Richarden_ZA
dc.date.accessioned2014-11-05T17:35:43Z
dc.date.available2014-11-05T17:35:43Z
dc.date.issued1996en_ZA
dc.descriptionBibliography: leaves 143-154.en_ZA
dc.description.abstractThe advent of cemented joint replacements has revolutionised the management of patients suffering from chronic arthritis. However, establishing a durable bond between the prosthesis and the surrounding bone remains a considerable problem. As a result, cementless implants have been developed. These components rely on the ingrowth of bone into a porous coating, which covers a portion of the component surface, to achieve the required mechanical interlock. Once mineralised bone tissue has formed within .the porous surface, a stable bond results which will be maintained by the normal bone turnover processes, thereby providing long term attachment. However, one of the problems associated with the use of cementless implants is the unpredictability of the extent of bone ingrowth. The process of osseo-integration is greatly influenced by the magnitude of the micro-motion between the implant and the surrounding bone. Large movements inhibit ingrowth, and may result in the formation of an interfacial fibrous tissue layer. In addition, interface strains will influence the early repair process and guide long term bone remodelling within this region. A numerical model for the prediction of bone formation within the porous surface has been developed. The evolution laws consider the early repair activity, possible fibrous tissue formation, and long term remodelling, as a function of the history of inelastic relative displacements and elastic interface strains. The model is based on the development of an isoparametric interface element, which is suitable for implementation into a non-linear finite element code. In the unbonded condition, the contact is governed by a Coulomb friction formulation. The position and shape of the Coulomb yield surface is altered according to the evolution equations, which govern the development of mineralised tissue within the surface porosity. The strain history and post-operative time are then used to develop a stimulus coefficient, which determines the course of the interface tissue development. If bone tissue is predicted, the subsequent interfacial material will be governed by a remodelling algorithm for the prediction of the long term response. If the bond strength is exceeded, fracture occurs and the joint may open or slide, thus returning to its original, unbonded, state. In the event of large micro-motions, the yield surface and material formulation are altered to include fibrous tissue. The model is used to predict the development of interfacial tissues at the porous surface of a tibial tray component, with a central peg and a PCA (Howmedica, Inc.) femoral stem. Although many factors influence interfacial tissue development, mechanical loads are assumed to be dominant. In the short term, the relationship between micro-motion and interface tissue response has been shown. However, long term remodelling of interfacial tissues has not been widely demonstrated and, therefore, additional experimental data is required to validate the current long term remodelling predictions.en_ZA
dc.identifier.apacitationStarke, G. R. (1996). <i>Numerical simulation of implant-bone interaction following cementless joint replacement</i>. (Thesis). University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Mechanical Engineering. Retrieved from http://hdl.handle.net/11427/9258en_ZA
dc.identifier.chicagocitationStarke, Gregory Richard. <i>"Numerical simulation of implant-bone interaction following cementless joint replacement."</i> Thesis., University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Mechanical Engineering, 1996. http://hdl.handle.net/11427/9258en_ZA
dc.identifier.citationStarke, G. 1996. Numerical simulation of implant-bone interaction following cementless joint replacement. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Starke, Gregory Richard AB - The advent of cemented joint replacements has revolutionised the management of patients suffering from chronic arthritis. However, establishing a durable bond between the prosthesis and the surrounding bone remains a considerable problem. As a result, cementless implants have been developed. These components rely on the ingrowth of bone into a porous coating, which covers a portion of the component surface, to achieve the required mechanical interlock. Once mineralised bone tissue has formed within .the porous surface, a stable bond results which will be maintained by the normal bone turnover processes, thereby providing long term attachment. However, one of the problems associated with the use of cementless implants is the unpredictability of the extent of bone ingrowth. The process of osseo-integration is greatly influenced by the magnitude of the micro-motion between the implant and the surrounding bone. Large movements inhibit ingrowth, and may result in the formation of an interfacial fibrous tissue layer. In addition, interface strains will influence the early repair process and guide long term bone remodelling within this region. A numerical model for the prediction of bone formation within the porous surface has been developed. The evolution laws consider the early repair activity, possible fibrous tissue formation, and long term remodelling, as a function of the history of inelastic relative displacements and elastic interface strains. The model is based on the development of an isoparametric interface element, which is suitable for implementation into a non-linear finite element code. In the unbonded condition, the contact is governed by a Coulomb friction formulation. The position and shape of the Coulomb yield surface is altered according to the evolution equations, which govern the development of mineralised tissue within the surface porosity. The strain history and post-operative time are then used to develop a stimulus coefficient, which determines the course of the interface tissue development. If bone tissue is predicted, the subsequent interfacial material will be governed by a remodelling algorithm for the prediction of the long term response. If the bond strength is exceeded, fracture occurs and the joint may open or slide, thus returning to its original, unbonded, state. In the event of large micro-motions, the yield surface and material formulation are altered to include fibrous tissue. The model is used to predict the development of interfacial tissues at the porous surface of a tibial tray component, with a central peg and a PCA (Howmedica, Inc.) femoral stem. Although many factors influence interfacial tissue development, mechanical loads are assumed to be dominant. In the short term, the relationship between micro-motion and interface tissue response has been shown. However, long term remodelling of interfacial tissues has not been widely demonstrated and, therefore, additional experimental data is required to validate the current long term remodelling predictions. DA - 1996 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1996 T1 - Numerical simulation of implant-bone interaction following cementless joint replacement TI - Numerical simulation of implant-bone interaction following cementless joint replacement UR - http://hdl.handle.net/11427/9258 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/9258
dc.identifier.vancouvercitationStarke GR. Numerical simulation of implant-bone interaction following cementless joint replacement. [Thesis]. University of Cape Town ,Faculty of Engineering & the Built Environment ,Department of Mechanical Engineering, 1996 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/9258en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Mechanical Engineeringen_ZA
dc.publisher.facultyFaculty of Engineering and the Built Environment
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMechanical Engineeringen_ZA
dc.titleNumerical simulation of implant-bone interaction following cementless joint replacementen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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