The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa

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dc.contributor.advisorLevitt, Dinkyen_ZA
dc.contributor.authorRoss, Ian Louisen_ZA
dc.date.accessioned2015-01-01T12:46:04Z
dc.date.available2015-01-01T12:46:04Z
dc.date.issued2011en_ZA
dc.descriptionIncludes abstract.en_ZA
dc.descriptionIncludes bibliographical references.en_ZA
dc.description.abstractThis thesis aimed to address a number of unanswered research questions in Addison's Disease: investigate whether autoimmunity is the predominant cause of Addison's disease in South Africa and if a human leukocyte (HLA) DQ antigen association exists; the extent to which lipids, lipoproteins and biochemical markers of cardiovascular disease are abnormal; the degree to which replacement doses of hydrocortisone are supra-physiological; the impact of glucocorticoid receptor (GCR) polymorphisms on risk factors, markers of cardiovascular disease and replacement doses of hydrocortisone.en_ZA
dc.identifier.apacitationRoss, I. L. (2011). <i>The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/10862en_ZA
dc.identifier.chicagocitationRoss, Ian Louis. <i>"The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2011. http://hdl.handle.net/11427/10862en_ZA
dc.identifier.citationRoss, I. 2011. The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Ross, Ian Louis AB - This thesis aimed to address a number of unanswered research questions in Addison's Disease: investigate whether autoimmunity is the predominant cause of Addison's disease in South Africa and if a human leukocyte (HLA) DQ antigen association exists; the extent to which lipids, lipoproteins and biochemical markers of cardiovascular disease are abnormal; the degree to which replacement doses of hydrocortisone are supra-physiological; the impact of glucocorticoid receptor (GCR) polymorphisms on risk factors, markers of cardiovascular disease and replacement doses of hydrocortisone. DA - 2011 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa TI - The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa UR - http://hdl.handle.net/11427/10862 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/10862
dc.identifier.vancouvercitationRoss IL. The aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africa. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2011 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/10862en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedicineen_ZA
dc.titleThe aetiopathogenesis, cardiovascular and metabolic complications, and pharmacogenomics of Addison's disease in South Africaen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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