In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid

Simple item page
dc.contributor.advisorChibale, Kellyen_ZA
dc.contributor.authorNjoroge, Mathewen_ZA
dc.date.accessioned2015-05-27T04:10:48Z
dc.date.available2015-05-27T04:10:48Z
dc.date.issued2014en_ZA
dc.descriptionIncludes bibliographical references.en_ZA
dc.description.abstractDrug metabolism is recognised as a key component of the drug discovery and development process. It exerts an influence on the action, duration of action and toxicity of a drug in vivo. The integration of drug metabolism studies is therefore crucial to compound progression through the various stages of the development process. This work details the in vitro metabolism work conducted during the early development of aminoquinoline tetrazoles, and derivatives of metergoline and fusidic acid as potential antiplasmodial and/or antimycobacterial agents.en_ZA
dc.identifier.apacitationNjoroge, M. (2014). <i>In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/12928en_ZA
dc.identifier.chicagocitationNjoroge, Mathew. <i>"In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 2014. http://hdl.handle.net/11427/12928en_ZA
dc.identifier.citationNjoroge, M. 2014. In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Njoroge, Mathew AB - Drug metabolism is recognised as a key component of the drug discovery and development process. It exerts an influence on the action, duration of action and toxicity of a drug in vivo. The integration of drug metabolism studies is therefore crucial to compound progression through the various stages of the development process. This work details the in vitro metabolism work conducted during the early development of aminoquinoline tetrazoles, and derivatives of metergoline and fusidic acid as potential antiplasmodial and/or antimycobacterial agents. DA - 2014 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid TI - In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid UR - http://hdl.handle.net/11427/12928 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/12928
dc.identifier.vancouvercitationNjoroge M. In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 2014 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12928en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Chemistryen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherChemistryen_ZA
dc.titleIn vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic aciden_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
thesis_sci_2014_njoroge_m.pdf
Size:
4.98 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
PhD / Doctoral