The iron-binding proteins of iron-absorbing rat intestinal mucosa

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dc.contributor.advisorPurvis, Langley Ren_ZA
dc.contributor.advisorJacobs, Peteren_ZA
dc.contributor.authorJohnson, Glynisen_ZA
dc.date.accessioned2018-02-05T12:36:42Z
dc.date.available2018-02-05T12:36:42Z
dc.date.issued1983en_ZA
dc.description.abstractIron deficiency anaemia is perhaps the most widespread nutritional deficiency disease; as result, the topic of iron absorption has received intensive investigation over a relatively long period of time. Most of the investigative thrust has come from clinical medicine and allied fields, with some associated biochemical investigation. Evidence from the latter has pointed towards the involvement of iron-binding proteins especially ferritin and transferrin in the absorptive process. While the biochemical literature on these two proteins, particularly transferrin, is vast, their roles in iron absorption are obscure. This study was undertaken, therefore, as an investigation into these proteins, their quantitation and role in iron absorption. The physiology of absorption was studied by injection of radiolabelled ferrous ascorbate into isolated intestinal loops and the determination of mucosal, blood and carcass uptake.en_ZA
dc.identifier.apacitationJohnson, G. (1983). <i>The iron-binding proteins of iron-absorbing rat intestinal mucosa</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Haematology. Retrieved from http://hdl.handle.net/11427/27263en_ZA
dc.identifier.chicagocitationJohnson, Glynis. <i>"The iron-binding proteins of iron-absorbing rat intestinal mucosa."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Haematology, 1983. http://hdl.handle.net/11427/27263en_ZA
dc.identifier.citationJohnson, G. 1983. The iron-binding proteins of iron-absorbing rat intestinal mucosa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Johnson, Glynis AB - Iron deficiency anaemia is perhaps the most widespread nutritional deficiency disease; as result, the topic of iron absorption has received intensive investigation over a relatively long period of time. Most of the investigative thrust has come from clinical medicine and allied fields, with some associated biochemical investigation. Evidence from the latter has pointed towards the involvement of iron-binding proteins especially ferritin and transferrin in the absorptive process. While the biochemical literature on these two proteins, particularly transferrin, is vast, their roles in iron absorption are obscure. This study was undertaken, therefore, as an investigation into these proteins, their quantitation and role in iron absorption. The physiology of absorption was studied by injection of radiolabelled ferrous ascorbate into isolated intestinal loops and the determination of mucosal, blood and carcass uptake. DA - 1983 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1983 T1 - The iron-binding proteins of iron-absorbing rat intestinal mucosa TI - The iron-binding proteins of iron-absorbing rat intestinal mucosa UR - http://hdl.handle.net/11427/27263 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/27263
dc.identifier.vancouvercitationJohnson G. The iron-binding proteins of iron-absorbing rat intestinal mucosa. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Haematology, 1983 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/27263en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Clinical Haematologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otheriron-binding proteinsen_ZA
dc.titleThe iron-binding proteins of iron-absorbing rat intestinal mucosaen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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