Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome

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dc.contributor.advisorBornman, PCen_ZA
dc.contributor.authorRadebold, Klausen_ZA
dc.date.accessioned2014-12-31T19:54:34Z
dc.date.available2014-12-31T19:54:34Z
dc.date.issued2000en_ZA
dc.descriptionIncludes bibliography.en_ZA
dc.description.abstractDespite major advances over the last two decades with the management of patients with Zollinger-Ellison syndrome (ZES), unanswered questions remain concerning the natural history of the disease, the impact of new diagnostics modalities on cure rates, and the role of surgery in the era of modem medical therapies. The aims of the thesis are to (i) analyse the database of 40 ZES patients treated at Groote Schuur Hospital (GSH) over two decades, with special reference to the impact of various surgical strategies on outcome, (ii) investigate a possible correlation between biological tissue marker expression and tumour behaviour, (iii) study the effect of somatostatin receptor scintigraphy (SRS) on surgical cure rates, and (iv) assess the efficacy and safety of a new proton pump inhibitor (pantoprazole) in controlling acid hypersecretion.en_ZA
dc.identifier.apacitationRadebold, K. (2000). <i>Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Surgery. Retrieved from http://hdl.handle.net/11427/10762en_ZA
dc.identifier.chicagocitationRadebold, Klaus. <i>"Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2000. http://hdl.handle.net/11427/10762en_ZA
dc.identifier.citationRadebold, K. 2000. Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Radebold, Klaus AB - Despite major advances over the last two decades with the management of patients with Zollinger-Ellison syndrome (ZES), unanswered questions remain concerning the natural history of the disease, the impact of new diagnostics modalities on cure rates, and the role of surgery in the era of modem medical therapies. The aims of the thesis are to (i) analyse the database of 40 ZES patients treated at Groote Schuur Hospital (GSH) over two decades, with special reference to the impact of various surgical strategies on outcome, (ii) investigate a possible correlation between biological tissue marker expression and tumour behaviour, (iii) study the effect of somatostatin receptor scintigraphy (SRS) on surgical cure rates, and (iv) assess the efficacy and safety of a new proton pump inhibitor (pantoprazole) in controlling acid hypersecretion. DA - 2000 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2000 T1 - Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome TI - Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome UR - http://hdl.handle.net/11427/10762 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/10762
dc.identifier.vancouvercitationRadebold K. Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Surgery, 2000 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/10762en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Surgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherSurgeryen_ZA
dc.titleEvaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndromeen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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