The reproductive health effects of along term DDT exposure on malaria vector control workers in Northern Province, South Africa
Doctoral Thesis
2002
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University of Cape Town
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Abstract
Metabolites of DDT (1, 1, 1-trichloro-2,2-bis(p-chlorophenyl)ethane), used in many developing countries including South Africa for the control of malaria vectors, have been shown to be endocrine disruptors in vitro and in vivo. The study hypothesis was that male vector control workers highly exposed to DDT in the past should demonstrate clinically significant exposure-related anti-androgenic and/or estrogenic effects reflected in abnormalities in hormone levels, semen, sexual function and fertility. A cross-sectional study of 60 workers from 3 camps situated near Malaria Control Center (MMC) in Tzaneen was performed.
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Includes bibliographical references.
Reference:
Dalvie, M. 2002. The reproductive health effects of along term DDT exposure on malaria vector control workers in Northern Province, South Africa. University of Cape Town.