The role of the CCR5 co-receptor conformation in HIV fusion

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dc.contributor.advisorFlanagan, Colleenen_ZA
dc.contributor.authorSalo, Alexen_ZA
dc.date.accessioned2014-07-28T14:55:59Z
dc.date.available2014-07-28T14:55:59Z
dc.date.issued2008en_ZA
dc.descriptionIncludes bibliographical references (leaves 71-80).
dc.description.abstractThis thesis aimed to better define the co-receptor conformation by determining whether mutants of the CCR5 receptor stabilized in the active conformation were less able to mediate HIV fussion. Eight mutant receptors were generated by site-directed mutagenesis and screened for constitutive activity using intracellutal signaling assays.en_ZA
dc.identifier.apacitationSalo, A. (2008). <i>The role of the CCR5 co-receptor conformation in HIV fusion</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry. Retrieved from http://hdl.handle.net/11427/3150en_ZA
dc.identifier.chicagocitationSalo, Alex. <i>"The role of the CCR5 co-receptor conformation in HIV fusion."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2008. http://hdl.handle.net/11427/3150en_ZA
dc.identifier.citationSalo, A. 2008. The role of the CCR5 co-receptor conformation in HIV fusion. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Salo, Alex AB - This thesis aimed to better define the co-receptor conformation by determining whether mutants of the CCR5 receptor stabilized in the active conformation were less able to mediate HIV fussion. Eight mutant receptors were generated by site-directed mutagenesis and screened for constitutive activity using intracellutal signaling assays. DA - 2008 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2008 T1 - The role of the CCR5 co-receptor conformation in HIV fusion TI - The role of the CCR5 co-receptor conformation in HIV fusion UR - http://hdl.handle.net/11427/3150 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3150
dc.identifier.vancouvercitationSalo A. The role of the CCR5 co-receptor conformation in HIV fusion. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2008 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3150en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Medical Biochemistryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedical Biochemistryen_ZA
dc.titleThe role of the CCR5 co-receptor conformation in HIV fusionen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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