Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses

dc.contributor.authorKatz, Woolf
dc.date.accessioned2020-06-02T11:34:41Z
dc.date.available2020-06-02T11:34:41Z
dc.date.issued1970
dc.date.updated2020-04-07T20:15:48Z
dc.description.abstractThe principal aim of this study was to develop a new bed material suitable for gel exclusion chromatography, which would embrace all the desirable characteristics of available materials used for this purpose and if possible improve on some of them. The two most important limitations of existing gel media concern their exclusion limits and rigidity. Agar and agarose have been found satisfactory for the separation of larger molecules including some viruses, but difficulties may arise at low gel concentrations due to the low mechanical strength of the granules. The dextran and polyacrylamide gels have in general a rigidity equal to that of agar and agarose, but cannot be prepared with such large pore sizes and are therefore limited to the separation of smaller molecules.
dc.identifier.apacitationKatz, W. (1970). <i>Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses</i>. (). ,Faculty of Health Sciences ,Division of Medical Virology. Retrieved from en_ZA
dc.identifier.chicagocitationKatz, Woolf. <i>"Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses."</i> ., ,Faculty of Health Sciences ,Division of Medical Virology, 1970. en_ZA
dc.identifier.citationKatz, W. 1970. Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses. . ,Faculty of Health Sciences ,Division of Medical Virology. en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Katz, Woolf AB - The principal aim of this study was to develop a new bed material suitable for gel exclusion chromatography, which would embrace all the desirable characteristics of available materials used for this purpose and if possible improve on some of them. The two most important limitations of existing gel media concern their exclusion limits and rigidity. Agar and agarose have been found satisfactory for the separation of larger molecules including some viruses, but difficulties may arise at low gel concentrations due to the low mechanical strength of the granules. The dextran and polyacrylamide gels have in general a rigidity equal to that of agar and agarose, but cannot be prepared with such large pore sizes and are therefore limited to the separation of smaller molecules. DA - 1970 DB - OpenUCT DP - University of Cape Town KW - Chromatography LK - https://open.uct.ac.za PY - 1970 T1 - Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses TI - Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses UR - ER - en_ZA
dc.identifier.urihttps://hdl.handle.net/11427/32028
dc.identifier.vancouvercitationKatz W. Tanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses. []. ,Faculty of Health Sciences ,Division of Medical Virology, 1970 [cited yyyy month dd]. Available from: en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDivision of Medical Virology
dc.publisher.facultyFaculty of Health Sciences
dc.subjectChromatography
dc.titleTanned gelatin: some biophysical and biochemical properties of a new gel exclusion agent and its application to the chromatography of proteins and viruses
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
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