Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon

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dc.contributor.authorHalle, Marieen_ZA
dc.contributor.authorTakongue, Christianen_ZA
dc.contributor.authorKengne, Andreen_ZA
dc.contributor.authorKaze, Francoisen_ZA
dc.contributor.authorNgu, Kathleenen_ZA
dc.date.accessioned2015-12-07T08:52:13Z
dc.date.available2015-12-07T08:52:13Z
dc.date.issued2015en_ZA
dc.description.abstractBACKGROUND: Data regarding the epidemiology of end-stage renal disease (ESRD) and dialysis in sub-Saharan Africa are scarce and knowledge about the spectrum renal disease is very limited. This study is on the profile of patients with ESRD in a referral hospital in Cameroon. METHODS: Medical records of patients with ESRD covering a 10-year period of activities of the Douala General Hospital were reviewed. Data were retrieved on socio demographic, and clinical data such as major comorbidities, the presumed aetiology of ESRD, blood pressure, biological variables and renal replacement therapy. RESULTS: In all 863 patients were included with 66% being men. Mean age was 47.4years overall, 48.9 in men and 44.5 in women (p<0.001). The main background aetiologies of ESRD were hypertension (30.9%), glomerulonephritis (15.8%), diabetes (15.9%), HIV (6.6%) and unknown (14.7%). Participants with HIV, glomerulonephritis or unknown background nephropathy were younger, more likely to be women, to be single and unemployed, while those with hypertension and/or diabetes were older, more likely to be men, to be either married or widow, and to be retired or working in the public sector. A total of 677 patients started haemodialysis with decreasing trend across age quartiles (p=009), and variation across background nephropathies (p<0.001). Emergency dialysis unplanned on a temporary catheter occurs in 88.3% of patients. CONCLUSION: This study has revealed substantial gender and age differentials in the socio-demographic features and background nephropathy in patients with ESRD in this setting. The likelihood of starting maintenance dialysis varied across background nephropathies, driven at least in part by age differences across background nephropathies.en_ZA
dc.identifier.apacitationHalle, M., Takongue, C., Kengne, A., Kaze, F., & Ngu, K. (2015). Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon. <i>BMC Nephrology</i>, http://hdl.handle.net/11427/15654en_ZA
dc.identifier.chicagocitationHalle, Marie, Christian Takongue, Andre Kengne, Francois Kaze, and Kathleen Ngu "Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon." <i>BMC Nephrology</i> (2015) http://hdl.handle.net/11427/15654en_ZA
dc.identifier.citationHalle, M. P., Takongue, C., Kengne, A. P., Kaze, F. F., & Ngu, K. B. (2015). Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon. BMC nephrology, 16(1), 59.en_ZA
dc.identifier.ris TY - Journal Article AU - Halle, Marie AU - Takongue, Christian AU - Kengne, Andre AU - Kaze, Francois AU - Ngu, Kathleen AB - BACKGROUND: Data regarding the epidemiology of end-stage renal disease (ESRD) and dialysis in sub-Saharan Africa are scarce and knowledge about the spectrum renal disease is very limited. This study is on the profile of patients with ESRD in a referral hospital in Cameroon. METHODS: Medical records of patients with ESRD covering a 10-year period of activities of the Douala General Hospital were reviewed. Data were retrieved on socio demographic, and clinical data such as major comorbidities, the presumed aetiology of ESRD, blood pressure, biological variables and renal replacement therapy. RESULTS: In all 863 patients were included with 66% being men. Mean age was 47.4years overall, 48.9 in men and 44.5 in women (p<0.001). The main background aetiologies of ESRD were hypertension (30.9%), glomerulonephritis (15.8%), diabetes (15.9%), HIV (6.6%) and unknown (14.7%). Participants with HIV, glomerulonephritis or unknown background nephropathy were younger, more likely to be women, to be single and unemployed, while those with hypertension and/or diabetes were older, more likely to be men, to be either married or widow, and to be retired or working in the public sector. A total of 677 patients started haemodialysis with decreasing trend across age quartiles (p=009), and variation across background nephropathies (p<0.001). Emergency dialysis unplanned on a temporary catheter occurs in 88.3% of patients. CONCLUSION: This study has revealed substantial gender and age differentials in the socio-demographic features and background nephropathy in patients with ESRD in this setting. The likelihood of starting maintenance dialysis varied across background nephropathies, driven at least in part by age differences across background nephropathies. DA - 2015 DB - OpenUCT DO - 10.1186/s12882-015-0044-2 DP - University of Cape Town J1 - BMC Nephrology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon TI - Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon UR - http://hdl.handle.net/11427/15654 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15654
dc.identifier.urihttp://dx.doi.org/10.1186/s12882-015-0044-2
dc.identifier.vancouvercitationHalle M, Takongue C, Kengne A, Kaze F, Ngu K. Epidemiological profile of patients with end stage renal disease in a referral hospital in Cameroon. BMC Nephrology. 2015; http://hdl.handle.net/11427/15654.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2015 Halle et al.; licensee BioMed Central.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/4.0en_ZA
dc.sourceBMC Nephrologyen_ZA
dc.source.urihttp://www.biomedcentral.com/bmcnephrol/en_ZA
dc.subject.otherend-stage renal disease (ESRD)en_ZA
dc.subject.otherdialysisen_ZA
dc.subject.otherrenal diseaseen_ZA
dc.titleEpidemiological profile of patients with end stage renal disease in a referral hospital in Cameroonen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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