The role of peptides as intermediates in protein metabolism

dc.contributor.advisorKench, J E
dc.contributor.authorBerman, Mervyn Clive
dc.date.accessioned2020-05-22T17:29:07Z
dc.date.available2020-05-22T17:29:07Z
dc.date.issued1964
dc.date.updated2020-04-06T17:38:47Z
dc.description.abstractThere is much evidence in the recent literature that peptides may be intermediates in normal protein biosynthesis. This has also been inferred from certain disease states and other conditions under which protein biosynthesis is blocked at some point, e.g. cadmium, amino acid analogues or (in bacteria) antibiotics. The literature covering this concept will be presented. The present studies have been carried out on children, who because they are suffering from chronic protein malnutrition have very much lowered rates of protein synthesis and breakdown. In this unfortunate, but natural experiment, it was hoped that some factor or factors derived from protein synthesis might be found which influenced the synthetic mechanism as a whole. Evidence from the literature has been summarized which concludes that urine, apart from being convenient to collect, is the biological fluid most likely to contain high concentrates of peptides which are released during cellular metabolism.
dc.identifier.apacitationBerman, M. C. (1964). <i>The role of peptides as intermediates in protein metabolism</i>. (). ,Faculty of Health Sciences ,Department of Pathology. Retrieved from en_ZA
dc.identifier.chicagocitationBerman, Mervyn Clive. <i>"The role of peptides as intermediates in protein metabolism."</i> ., ,Faculty of Health Sciences ,Department of Pathology, 1964. en_ZA
dc.identifier.citationBerman, M.C. 1964. The role of peptides as intermediates in protein metabolism. . ,Faculty of Health Sciences ,Department of Pathology. en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Berman, Mervyn Clive AB - There is much evidence in the recent literature that peptides may be intermediates in normal protein biosynthesis. This has also been inferred from certain disease states and other conditions under which protein biosynthesis is blocked at some point, e.g. cadmium, amino acid analogues or (in bacteria) antibiotics. The literature covering this concept will be presented. The present studies have been carried out on children, who because they are suffering from chronic protein malnutrition have very much lowered rates of protein synthesis and breakdown. In this unfortunate, but natural experiment, it was hoped that some factor or factors derived from protein synthesis might be found which influenced the synthetic mechanism as a whole. Evidence from the literature has been summarized which concludes that urine, apart from being convenient to collect, is the biological fluid most likely to contain high concentrates of peptides which are released during cellular metabolism. DA - 1964 DB - OpenUCT DP - University of Cape Town KW - Peptides KW - protein biosynthesis LK - https://open.uct.ac.za PY - 1964 T1 - The role of peptides as intermediates in protein metabolism TI - The role of peptides as intermediates in protein metabolism UR - ER - en_ZA
dc.identifier.urihttps://hdl.handle.net/11427/31984
dc.identifier.vancouvercitationBerman MC. The role of peptides as intermediates in protein metabolism. []. ,Faculty of Health Sciences ,Department of Pathology, 1964 [cited yyyy month dd]. Available from: en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Pathology
dc.publisher.facultyFaculty of Health Sciences
dc.subjectPeptides
dc.subjectprotein biosynthesis
dc.titleThe role of peptides as intermediates in protein metabolism
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
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