An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines

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dc.contributor.advisorChege, Geralden_ZA
dc.contributor.advisorWilliamson, Anna-Liseen_ZA
dc.contributor.authorSingh, Vedanthaen_ZA
dc.date.accessioned2014-07-28T08:21:55Z
dc.date.available2014-07-28T08:21:55Z
dc.date.issued2013en_ZA
dc.descriptionIncludes abstract.
dc.descriptionIncludes bibliographical references.
dc.description.abstractPrevious studies from the HIV Vaccine Development Group at the University of Cape Town have reported that immunisation with recombinant modified vaccinia Ankara (SAAVI MVA-C) or DNA prime and Pr55 Gag virus-like particle (VLP) boost based on HIV-1 subtype C are able to successfully induce vaccine specific responses in Chacma baboons. The aim of the current study was to characterise the T cell memory phenotype distribution in peripheral mononuclear cells (PBMCs) isolated from Chacma baboons vaccinated with SAAVI MVA-C/VLP and DNA/VLP prime-boost vaccination regimens by flow cytometry.en_ZA
dc.identifier.apacitationSingh, V. (2013). <i>An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Virology. Retrieved from http://hdl.handle.net/11427/2738en_ZA
dc.identifier.chicagocitationSingh, Vedantha. <i>"An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Virology, 2013. http://hdl.handle.net/11427/2738en_ZA
dc.identifier.citationSingh, V. 2013. An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Singh, Vedantha AB - Previous studies from the HIV Vaccine Development Group at the University of Cape Town have reported that immunisation with recombinant modified vaccinia Ankara (SAAVI MVA-C) or DNA prime and Pr55 Gag virus-like particle (VLP) boost based on HIV-1 subtype C are able to successfully induce vaccine specific responses in Chacma baboons. The aim of the current study was to characterise the T cell memory phenotype distribution in peripheral mononuclear cells (PBMCs) isolated from Chacma baboons vaccinated with SAAVI MVA-C/VLP and DNA/VLP prime-boost vaccination regimens by flow cytometry. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines TI - An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines UR - http://hdl.handle.net/11427/2738 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/2738
dc.identifier.vancouvercitationSingh V. An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Virology, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/2738en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Virologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedicineen_ZA
dc.titleAn investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccinesen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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