Dietry and microbiological investigation in South African black and white subjects as a key to understanding the difference in the incidence of kidney stone disease in the two race groups

Doctoral Thesis

2003

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University of Cape Town

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Abstract
Kidney stones occur in the South African white population to the same extent as in other westem countries. However, the incidence of this disease in the South African black population is extremely rare. In this thesis, investigations were undertaken to establish whether different renal handling mechanisms occur in the two race groups in response to different dietary challenges and whether there might be qualitative and quantitative differences in the colonization and utilization of oxalate-degrading bacteria in the two race groups which might account for this phenomenon.
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