The intersection of the HIV epidemic and blood donation in South Africa

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dc.contributor.advisorLouw, Vernon
dc.contributor.advisorMaartens, Gary
dc.contributor.advisorMurphy, Edward
dc.contributor.advisorHughes, Shana
dc.contributor.authorVan Den Berg, Karin
dc.date.accessioned2025-03-31T07:33:45Z
dc.date.available2025-03-31T07:33:45Z
dc.date.issued2024
dc.date.updated2025-03-31T07:28:30Z
dc.description.abstractSouth Africa's large population of people living with HIV (PLWH) affects the local blood transfusion services (BTS) in multiple ways, including the recruitment of safe donors, the demand for blood and the development of blood safety policies. The latter includes the deferral of persons at risk of recently acquired HIV and sensitive testing for HIV antibodies and RNA. Estimating HIV incidence in blood donors is a key measure of successful prevention strategies. Blood donation by PLWH on antiretroviral therapy (ART) was identified as an emerging risk to blood safety as early ART initiation may result in delayed seroconversion, seroreversion, and prolonged suppression of viral replication which may escape detection by HIV antibody and nucleic acid amplification testing (NAT). My PhD research used epidemiologic, incidence modelling and mixed-method qualitative research techniques to assess the impact of undisclosed ART use among blood donors on the safety of the country's blood supply.
dc.identifier.apacitationVan Den Berg, K. (2024). <i>The intersection of the HIV epidemic and blood donation in South Africa</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/41294en_ZA
dc.identifier.chicagocitationVan Den Berg, Karin. <i>"The intersection of the HIV epidemic and blood donation in South Africa."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2024. http://hdl.handle.net/11427/41294en_ZA
dc.identifier.citationVan Den Berg, K. 2024. The intersection of the HIV epidemic and blood donation in South Africa. . University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. http://hdl.handle.net/11427/41294en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Van Den Berg, Karin AB - South Africa's large population of people living with HIV (PLWH) affects the local blood transfusion services (BTS) in multiple ways, including the recruitment of safe donors, the demand for blood and the development of blood safety policies. The latter includes the deferral of persons at risk of recently acquired HIV and sensitive testing for HIV antibodies and RNA. Estimating HIV incidence in blood donors is a key measure of successful prevention strategies. Blood donation by PLWH on antiretroviral therapy (ART) was identified as an emerging risk to blood safety as early ART initiation may result in delayed seroconversion, seroreversion, and prolonged suppression of viral replication which may escape detection by HIV antibody and nucleic acid amplification testing (NAT). My PhD research used epidemiologic, incidence modelling and mixed-method qualitative research techniques to assess the impact of undisclosed ART use among blood donors on the safety of the country's blood supply. DA - 2024 DB - OpenUCT DP - University of Cape Town KW - HIV KW - Blood donation LK - https://open.uct.ac.za PB - University of Cape Town PY - 2024 T1 - The intersection of the HIV epidemic and blood donation in South Africa TI - The intersection of the HIV epidemic and blood donation in South Africa UR - http://hdl.handle.net/11427/41294 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/41294
dc.identifier.vancouvercitationVan Den Berg K. The intersection of the HIV epidemic and blood donation in South Africa. []. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2024 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/41294en_ZA
dc.language.isoen
dc.language.rfc3066ENG
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.publisher.institutionUniversity of Cape Town
dc.subjectHIV
dc.subjectBlood donation
dc.titleThe intersection of the HIV epidemic and blood donation in South Africa
dc.typeThesis / Dissertation
dc.type.qualificationlevelDoctoral
dc.type.qualificationlevelPhD
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