The potential effect of an HIV/AIDS vaccine in South Africa

dc.contributor.authorDorrington, R E
dc.contributor.authorJohnson, L F
dc.date.accessioned2017-05-25T12:18:56Z
dc.date.available2017-05-25T12:18:56Z
dc.date.issued2007
dc.date.updated2016-01-08T10:05:58Z
dc.description.abstractThis paper presents a model for assessing the potential effect of an HIV/AIDS vaccine in South Africa, and for calculating the amount of vaccine that would be required. A number of different hypothetical vaccine profiles and vaccine distribution strategies are considered. Results suggest that a sterilising vaccine could reduce the HIV incidence between 2015 and 2025 by up to 50%, while a disease modifying vaccine would be unlikely to reduce HIV incidence by more than a third. The effect on AIDS mortality over the same period would be substantially smaller, and it is unlikely that any preventive vaccine would reduce AIDS mortality by more than 10% between 2015 and 2025.
dc.identifier.apacitationDorrington, R. E., & Johnson, L. F. (2007). The potential effect of an HIV/AIDS vaccine in South Africa. <i>South African Actuarial Journal</i>, http://hdl.handle.net/11427/24410en_ZA
dc.identifier.chicagocitationDorrington, R E, and L F Johnson "The potential effect of an HIV/AIDS vaccine in South Africa." <i>South African Actuarial Journal</i> (2007) http://hdl.handle.net/11427/24410en_ZA
dc.identifier.citationJohnson, L. F., & Dorrington, R. E. (2007). The potential effect of an HIV/AIDS vaccine in South Africa. South African Actuarial Journal, 7(1), 49-72.
dc.identifier.ris TY - Journal Article AU - Dorrington, R E AU - Johnson, L F AB - This paper presents a model for assessing the potential effect of an HIV/AIDS vaccine in South Africa, and for calculating the amount of vaccine that would be required. A number of different hypothetical vaccine profiles and vaccine distribution strategies are considered. Results suggest that a sterilising vaccine could reduce the HIV incidence between 2015 and 2025 by up to 50%, while a disease modifying vaccine would be unlikely to reduce HIV incidence by more than a third. The effect on AIDS mortality over the same period would be substantially smaller, and it is unlikely that any preventive vaccine would reduce AIDS mortality by more than 10% between 2015 and 2025. DA - 2007 DB - OpenUCT DP - University of Cape Town J1 - South African Actuarial Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2007 T1 - The potential effect of an HIV/AIDS vaccine in South Africa TI - The potential effect of an HIV/AIDS vaccine in South Africa UR - http://hdl.handle.net/11427/24410 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24410
dc.identifier.vancouvercitationDorrington RE, Johnson LF. The potential effect of an HIV/AIDS vaccine in South Africa. South African Actuarial Journal. 2007; http://hdl.handle.net/11427/24410.en_ZA
dc.language.isoeng
dc.publisher.departmentCentre for Actuarial Research (CARE)en_ZA
dc.publisher.facultyFaculty of Commerceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceSouth African Actuarial Journal
dc.source.urihttp://www.actuarialsociety.org.za/Professionalresources/SAActuarialJournal.aspx
dc.titleThe potential effect of an HIV/AIDS vaccine in South Africa
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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