Characteristics and outcomes of acute heart failure in sub Saharan Africa

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dc.contributor.advisorSliwa, Karenen_ZA
dc.contributor.advisorCotter, Gaden_ZA
dc.contributor.authorSani, Mahmoud Umaren_ZA
dc.date.accessioned2017-01-31T09:16:20Z
dc.date.available2017-01-31T09:16:20Z
dc.date.issued2016en_ZA
dc.description.abstractThe main objective of this thesis was to study the clinical characteristics and short-term (6 months) outcome of acute heart failure as well as determine the role of conventional biomarker BNP and the novel biomarker Gal3 in the prognostication of acute heart failure patients. To achieve this, we investigated in the first cohort; 1) the demographic and clinical characteristic of patients with AHF, 2) their echocardiographic parameters and how they predict outcome, 3) the predictors of readmission and mortality, 4) the prevalence and impact of renal dysfunction on AHF and 5) the electrocardiographic pattern in AHF. The outcome measures were worsening renal function (WRF), length of hospital stay, HF readmissions and cardiovascular death within 60 days and all cause, cardiovascular or HF death through 180 days. In the second cohort, we investigated the demographics, clinical characteristics as well as the relationship between plasma levels of BNP and galectin 3 and outcomes (cardiovascular (CV) death or HF hospitalization through week 24) as well as the relationship between the plasma levels of BNP and Gal3 and both left ventricular (LV) and right ventricular (RV) remodeling in patients with AHF.en_ZA
dc.identifier.apacitationSani, M. U. (2016). <i>Characteristics and outcomes of acute heart failure in sub Saharan Africa</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/23778en_ZA
dc.identifier.chicagocitationSani, Mahmoud Umar. <i>"Characteristics and outcomes of acute heart failure in sub Saharan Africa."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2016. http://hdl.handle.net/11427/23778en_ZA
dc.identifier.citationSani, M. 2016. Characteristics and outcomes of acute heart failure in sub Saharan Africa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Sani, Mahmoud Umar AB - The main objective of this thesis was to study the clinical characteristics and short-term (6 months) outcome of acute heart failure as well as determine the role of conventional biomarker BNP and the novel biomarker Gal3 in the prognostication of acute heart failure patients. To achieve this, we investigated in the first cohort; 1) the demographic and clinical characteristic of patients with AHF, 2) their echocardiographic parameters and how they predict outcome, 3) the predictors of readmission and mortality, 4) the prevalence and impact of renal dysfunction on AHF and 5) the electrocardiographic pattern in AHF. The outcome measures were worsening renal function (WRF), length of hospital stay, HF readmissions and cardiovascular death within 60 days and all cause, cardiovascular or HF death through 180 days. In the second cohort, we investigated the demographics, clinical characteristics as well as the relationship between plasma levels of BNP and galectin 3 and outcomes (cardiovascular (CV) death or HF hospitalization through week 24) as well as the relationship between the plasma levels of BNP and Gal3 and both left ventricular (LV) and right ventricular (RV) remodeling in patients with AHF. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - Characteristics and outcomes of acute heart failure in sub Saharan Africa TI - Characteristics and outcomes of acute heart failure in sub Saharan Africa UR - http://hdl.handle.net/11427/23778 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/23778
dc.identifier.vancouvercitationSani MU. Characteristics and outcomes of acute heart failure in sub Saharan Africa. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/23778en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedicineen_ZA
dc.titleCharacteristics and outcomes of acute heart failure in sub Saharan Africaen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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