Towards designing de novo (1--->4)-linked polysaccharides

Chen, Jeff Yu-Jen

Towards designing de novo (1--->4)-linked polysaccharides

Thesis / Dissertation

2004

Abstract

Carbohydrates are invaluable in a variety of industrial applications ranging from biodegradable materials to pharmaceutical drug carriers. Small functional groups, such as hydroxyl, amine, N-acetylamide and methoxy are commonly employed for creating de novo saccharides with enhanced functionality. The physiochemical properties of carbohydrates are governed by their conformations and the polarity of their substituents strongly influences the overall flexibility of such biomolecules. In this thesis, two types of (1--->4)-inter-glycosidic interactions, viz. hydrogen bonding and hydrophobic effects, are investigated.

Keywords

Chemistry

Reference:

Collections

PhD / Doctoral

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