Differentially expressed genes in oesophageal cancer

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dc.contributor.advisorParker, Iqbal
dc.contributor.advisorHendricks, Denver T
dc.contributor.authorWamunyokoli, Fred Alexander Wafula
dc.date.accessioned2024-11-15T10:08:29Z
dc.date.available2024-11-15T10:08:29Z
dc.date.issued2002
dc.date.updated2024-08-13T14:18:53Z
dc.description.abstractOesophageal cancer (OC) is a leading cause of cancer death in the black population in South Africa. The lifetime risk of the disease amongst black males is 1 in 59. High incidence areas are the Transkei, Ciskei and KwaZulu-Natal where it is responsible for over 45 of all malignancies. Cancer develops through a multistep process of genomic instability of clonal evolution. Several oncogenes, tumour suppressor genes and transcription factors have been shown to be altered in oesophageal cancer. Their role however, in the development and/or susceptibility to the development of oesophageal cancer is poorly understood. The aim if this project is to identify candidate genes that are differentially expressed in oesophageal cancer patients with a view to understanding the development of oesophageal cancer. The ultimate objective of the project is to use this data to develop possible biomarkers for the disease.
dc.identifier.apacitationWamunyokoli, F. A. W. (2002). <i>ETD: Differentially expressed genes in oesophageal cancer</i>. (). ,Faculty of Health Sciences ,Division of Medical Biochemistry. Retrieved from http://hdl.handle.net/11427/40709en_ZA
dc.identifier.chicagocitationWamunyokoli, Fred Alexander Wafula. <i>"ETD: Differentially expressed genes in oesophageal cancer."</i> ., ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2002. http://hdl.handle.net/11427/40709en_ZA
dc.identifier.citationWamunyokoli, F.A.W. 2002. ETD: Differentially expressed genes in oesophageal cancer. . ,Faculty of Health Sciences ,Division of Medical Biochemistry. http://hdl.handle.net/11427/40709en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Wamunyokoli, Fred Alexander Wafula AB - Oesophageal cancer (OC) is a leading cause of cancer death in the black population in South Africa. The lifetime risk of the disease amongst black males is 1 in 59. High incidence areas are the Transkei, Ciskei and KwaZulu-Natal where it is responsible for over 45 of all malignancies. Cancer develops through a multistep process of genomic instability of clonal evolution. Several oncogenes, tumour suppressor genes and transcription factors have been shown to be altered in oesophageal cancer. Their role however, in the development and/or susceptibility to the development of oesophageal cancer is poorly understood. The aim if this project is to identify candidate genes that are differentially expressed in oesophageal cancer patients with a view to understanding the development of oesophageal cancer. The ultimate objective of the project is to use this data to develop possible biomarkers for the disease. DA - 2002 DB - OpenUCT DP - University of Cape Town KW - Medical Biochemistry LK - https://open.uct.ac.za PY - 2002 T1 - ETD: Differentially expressed genes in oesophageal cancer TI - ETD: Differentially expressed genes in oesophageal cancer UR - http://hdl.handle.net/11427/40709 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/40709
dc.identifier.vancouvercitationWamunyokoli FAW. ETD: Differentially expressed genes in oesophageal cancer. []. ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2002 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/40709en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDivision of Medical Biochemistry
dc.publisher.facultyFaculty of Health Sciences
dc.publisher.institutionUniversity of Cape Town
dc.subjectMedical Biochemistry
dc.titleDifferentially expressed genes in oesophageal cancer
dc.typeThesis / Dissertation
dc.type.qualificationlevelDoctoral
dc.type.qualificationlevelPhD
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