A study of lipids from animal skin secretions

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dc.contributor.advisorPugh, Wen_ZA
dc.contributor.advisorHolliman, F Gen_ZA
dc.contributor.advisorRapson, W Sen_ZA
dc.contributor.authorHougen, Frithjof Wilhelmen_ZA
dc.date.accessioned2016-10-24T03:50:40Z
dc.date.available2016-10-24T03:50:40Z
dc.date.issued1955en_ZA
dc.description.abstractWithin the akin of animals are situated various glands which secrete their products to the outer surface of the skin. The glands exist in many forms and their functions are diverse. A satisfactory classification based on the morphology of the glands has been worked out and the glands of the vertebrata are recognised as belonging to three main types: - holocrine, eccrine and apocrine glands. In man the holocrine glands are referred to as sebaceous and the eccrine as sudoriferous or sweat glands. These terms are often used also for animals. Comparatively few animal skin glands or secretions have been investigated chemically. The sebaceous secretion of the sheep, wool wax, has been much investigated owing to the commercial value of this product; and the author participated for some years in studies of wool wax at the National Chemical Research Laboratory, Pretoria. In Chapter I is summarised the present knowledge of wool wax chemistry, including contributions from this laboratory into the investigation of dihydric alcohols and hydroxy-acids and the syntheses of iso-acids which occur in wool wax. Skin secretions which have no commercial applications are nevertheless of great interest from a physiological and biochemical point of view. In this respect human skin secretions may naturally attract more attention than those of other animals. Their investigation may prove rewarding in throwing further light upon the studies of dermatological disorders in general, and more particularly upon the all-important problem of skin cancer. A study of human sebaceous secretions was taken up in this laboratory by the author; the aliphatic alcohols and some polycyclic hydrocarbons present were investigated. The chemistry of human sebaceous secretions is reviewed in Chapter II. Chapter III reviews work of other investigators on various skin gland secretions. The "scent" glands of musk deer and other animals and the "preen" glands of some birds have been investigated. Some materials of human origin such as ear wax, which are considered as related to sebaceous secretions, are included in this review. Natural fats and waxes are generally of complex composition and early workers did not succeed in isolating many pure components from such materials. As a result of improved techniques and methods considerable progress has been made in the last few years towards the elucidation of the fine structures of fats and waxes.en_ZA
dc.identifier.apacitationHougen, F. W. (1955). <i>A study of lipids from animal skin secretions</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/22278en_ZA
dc.identifier.chicagocitationHougen, Frithjof Wilhelm. <i>"A study of lipids from animal skin secretions."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 1955. http://hdl.handle.net/11427/22278en_ZA
dc.identifier.citationHougen, F. 1955. A study of lipids from animal skin secretions. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hougen, Frithjof Wilhelm AB - Within the akin of animals are situated various glands which secrete their products to the outer surface of the skin. The glands exist in many forms and their functions are diverse. A satisfactory classification based on the morphology of the glands has been worked out and the glands of the vertebrata are recognised as belonging to three main types: - holocrine, eccrine and apocrine glands. In man the holocrine glands are referred to as sebaceous and the eccrine as sudoriferous or sweat glands. These terms are often used also for animals. Comparatively few animal skin glands or secretions have been investigated chemically. The sebaceous secretion of the sheep, wool wax, has been much investigated owing to the commercial value of this product; and the author participated for some years in studies of wool wax at the National Chemical Research Laboratory, Pretoria. In Chapter I is summarised the present knowledge of wool wax chemistry, including contributions from this laboratory into the investigation of dihydric alcohols and hydroxy-acids and the syntheses of iso-acids which occur in wool wax. Skin secretions which have no commercial applications are nevertheless of great interest from a physiological and biochemical point of view. In this respect human skin secretions may naturally attract more attention than those of other animals. Their investigation may prove rewarding in throwing further light upon the studies of dermatological disorders in general, and more particularly upon the all-important problem of skin cancer. A study of human sebaceous secretions was taken up in this laboratory by the author; the aliphatic alcohols and some polycyclic hydrocarbons present were investigated. The chemistry of human sebaceous secretions is reviewed in Chapter II. Chapter III reviews work of other investigators on various skin gland secretions. The "scent" glands of musk deer and other animals and the "preen" glands of some birds have been investigated. Some materials of human origin such as ear wax, which are considered as related to sebaceous secretions, are included in this review. Natural fats and waxes are generally of complex composition and early workers did not succeed in isolating many pure components from such materials. As a result of improved techniques and methods considerable progress has been made in the last few years towards the elucidation of the fine structures of fats and waxes. DA - 1955 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1955 T1 - A study of lipids from animal skin secretions TI - A study of lipids from animal skin secretions UR - http://hdl.handle.net/11427/22278 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/22278
dc.identifier.vancouvercitationHougen FW. A study of lipids from animal skin secretions. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 1955 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/22278en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Chemistryen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherChemistryen_ZA
dc.titleA study of lipids from animal skin secretionsen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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