DNA repair in Bacteroides fragilis Bf-2

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dc.contributor.advisorWoods, David Ren_ZA
dc.contributor.advisorJones, David Ten_ZA
dc.contributor.authorAbratt, Valerie Roseen_ZA
dc.date.accessioned2016-09-20T12:30:53Z
dc.date.available2016-09-20T12:30:53Z
dc.date.issued1987en_ZA
dc.descriptionBibliography:pages 157-175.en_ZA
dc.description.abstractRepair deficient mutants of Bacteroides fragilis have been isolated in order to study the responses of this organism to various DNA damaging agents at the physiological and molecular levels. Two types of mutants were isolated by ethyl methane sulphonate mutagenesis of B.fragilis followed by selection for sensitivity to mitomycin C. One mutant (UVS9) showed sensitivity to both mitomycin C and far-UV irradiation. The other (MTC25) was more sensitive to mitomycin C than UVS9, but showed wild-type resistance to UV radiation. Both mutant strains had wild-type resistance to methyl methane sulphonate.en_ZA
dc.identifier.apacitationAbratt, V. R. (1987). <i>DNA repair in Bacteroides fragilis Bf-2</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/21823en_ZA
dc.identifier.chicagocitationAbratt, Valerie Rose. <i>"DNA repair in Bacteroides fragilis Bf-2."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 1987. http://hdl.handle.net/11427/21823en_ZA
dc.identifier.citationAbratt, V. 1987. DNA repair in Bacteroides fragilis Bf-2. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Abratt, Valerie Rose AB - Repair deficient mutants of Bacteroides fragilis have been isolated in order to study the responses of this organism to various DNA damaging agents at the physiological and molecular levels. Two types of mutants were isolated by ethyl methane sulphonate mutagenesis of B.fragilis followed by selection for sensitivity to mitomycin C. One mutant (UVS9) showed sensitivity to both mitomycin C and far-UV irradiation. The other (MTC25) was more sensitive to mitomycin C than UVS9, but showed wild-type resistance to UV radiation. Both mutant strains had wild-type resistance to methyl methane sulphonate. DA - 1987 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1987 T1 - DNA repair in Bacteroides fragilis Bf-2 TI - DNA repair in Bacteroides fragilis Bf-2 UR - http://hdl.handle.net/11427/21823 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/21823
dc.identifier.vancouvercitationAbratt VR. DNA repair in Bacteroides fragilis Bf-2. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 1987 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/21823en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Molecular and Cell Biologyen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherBacteriaen_ZA
dc.subject.otherDNAen_ZA
dc.subject.otherMolecular and Cell Biologyen_ZA
dc.titleDNA repair in Bacteroides fragilis Bf-2en_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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