The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis

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dc.contributor.advisorLang, Dirk Men_ZA
dc.contributor.authorHsu, Nai-Jenen_ZA
dc.date.accessioned2014-07-28T18:16:48Z
dc.date.available2014-07-28T18:16:48Z
dc.date.issued2007en_ZA
dc.descriptionIncludes bibliographical references (leaves 115-128).
dc.description.abstractGenerally, the factors contributing to success or failure of axon regeneration lie in the intrinsic properties of the injured neurons, as well as the surrounding microenvironment of the transected axon. Mammalian neurons may lack the intrinsic ability to survive after trauma, or to re-express genes required for axonal regrowth. Moreover, several proteins inhibitory to neurite growth, such as Tenascin-R (TN-R) and Nogo-A, have been identified in mammals. These proteins are associated with oligodendrocytes and myelin and are considered major inhibitory components of the CNS environment.en_ZA
dc.identifier.apacitationHsu, N. (2007). <i>The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Human Biology. Retrieved from http://hdl.handle.net/11427/3249en_ZA
dc.identifier.chicagocitationHsu, Nai-Jen. <i>"The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Human Biology, 2007. http://hdl.handle.net/11427/3249en_ZA
dc.identifier.citationHsu, N. 2007. The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hsu, Nai-Jen AB - Generally, the factors contributing to success or failure of axon regeneration lie in the intrinsic properties of the injured neurons, as well as the surrounding microenvironment of the transected axon. Mammalian neurons may lack the intrinsic ability to survive after trauma, or to re-express genes required for axonal regrowth. Moreover, several proteins inhibitory to neurite growth, such as Tenascin-R (TN-R) and Nogo-A, have been identified in mammals. These proteins are associated with oligodendrocytes and myelin and are considered major inhibitory components of the CNS environment. DA - 2007 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2007 T1 - The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis TI - The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis UR - http://hdl.handle.net/11427/3249 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3249
dc.identifier.vancouvercitationHsu N. The expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevis. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Human Biology, 2007 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3249en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Human Biologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherHuman Biologyen_ZA
dc.titleThe expression and functional analysis of neurite outgrowth inhibitors in the nervous system of Xenopus laevisen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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