The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance

dc.contributor.authorGunning, Mark Gerard
dc.date.accessioned2024-07-04T13:35:16Z
dc.date.available2024-07-04T13:35:16Z
dc.date.issued1999
dc.date.updated2024-07-04T12:50:11Z
dc.description.abstractPatients with impaired left ventricular function have a poor prognosis. Those with three vessel coronary artery disease who successfully undergo revascularisation have a better outlook but their peri-operative risk is high. Viable myocardium with impaired coronary flow reserve and impaired contractility recovers function following revascularisation and the preoperative identification of this "hibernating myocardium" helps to select those patients most likely to benefit from surgery. The accurate differentiation of hibernating tissue from full thickness myocardial scar is important as the choice of the correct treatment for patients with or without evidence of hibernation has important prognostic implications. This work comprises five studies which evaluate the comparison of imaging techniques for the identification of myocardial hibernation, the histological features which characterise hibernating tissue when compared to normal myocardium or scar, and the relationship of histology to imaging characteristics, and finally the clinical impact of revascularising hibernating myocardium when compared with medical treatment alone.
dc.identifier.apacitationGunning, M. G. (1999). <i>The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance</i>. (). ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/40260en_ZA
dc.identifier.chicagocitationGunning, Mark Gerard. <i>"The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance."</i> ., ,Faculty of Health Sciences ,Department of Medicine, 1999. http://hdl.handle.net/11427/40260en_ZA
dc.identifier.citationGunning, M.G. 1999. The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance. . ,Faculty of Health Sciences ,Department of Medicine. http://hdl.handle.net/11427/40260en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Gunning, Mark Gerard AB - Patients with impaired left ventricular function have a poor prognosis. Those with three vessel coronary artery disease who successfully undergo revascularisation have a better outlook but their peri-operative risk is high. Viable myocardium with impaired coronary flow reserve and impaired contractility recovers function following revascularisation and the preoperative identification of this "hibernating myocardium" helps to select those patients most likely to benefit from surgery. The accurate differentiation of hibernating tissue from full thickness myocardial scar is important as the choice of the correct treatment for patients with or without evidence of hibernation has important prognostic implications. This work comprises five studies which evaluate the comparison of imaging techniques for the identification of myocardial hibernation, the histological features which characterise hibernating tissue when compared to normal myocardium or scar, and the relationship of histology to imaging characteristics, and finally the clinical impact of revascularising hibernating myocardium when compared with medical treatment alone. DA - 1999 DB - OpenUCT DP - University of Cape Town KW - Medicine LK - https://open.uct.ac.za PY - 1999 T1 - The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance TI - The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance UR - http://hdl.handle.net/11427/40260 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/40260
dc.identifier.vancouvercitationGunning MG. The characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance. []. ,Faculty of Health Sciences ,Department of Medicine, 1999 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/40260en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.subjectMedicine
dc.titleThe characterisation of hibernating myocardium : a study of imaging techniques, histological features and clinical relevance
dc.typeThesis / Dissertation
dc.type.qualificationlevelDoctoral
dc.type.qualificationlevelMD
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