Aspects of structure-activity relationships and physiology of gastrin and related peptides

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dc.contributor.advisorVinik, Aaron I
dc.contributor.authorNapier, Beverley Jean
dc.date.accessioned2020-06-10T07:47:51Z
dc.date.available2020-06-10T07:47:51Z
dc.date.issued1978
dc.date.updated2020-04-09T09:48:40Z
dc.description.abstractWhen, in 1973, I embarked upon this study, the hormone gastrin seemed a suitable hormone to study with regard to investigation of structure-activity relationships and physiology of a peptide hormone. Gastrin was best known at that stage as a linear peptide comprising 17 amino acids, which was stable at room temperature and was resistant to degradation by vigorous treatments such as boiling {Gregory and Tracy, 1964; Berson and Yalow, 1971; Yalow and Berson, 1972) and pH extremes (Piszkiewicz, 1974). Such a molecule could thus be studied at room temperature, using conventional biochemical techniques, without the need for any special precautions to preserve its integrity.
dc.identifier.apacitationNapier, B. J. (1978). <i>Aspects of structure-activity relationships and physiology of gastrin and related peptides</i>. (). ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/32048en_ZA
dc.identifier.chicagocitationNapier, Beverley Jean. <i>"Aspects of structure-activity relationships and physiology of gastrin and related peptides."</i> ., ,Faculty of Health Sciences ,Department of Medicine, 1978. http://hdl.handle.net/11427/32048en_ZA
dc.identifier.citationNapier, B.J. 1978. Aspects of structure-activity relationships and physiology of gastrin and related peptides. . ,Faculty of Health Sciences ,Department of Medicine. http://hdl.handle.net/11427/32048en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Napier, Beverley Jean AB - When, in 1973, I embarked upon this study, the hormone gastrin seemed a suitable hormone to study with regard to investigation of structure-activity relationships and physiology of a peptide hormone. Gastrin was best known at that stage as a linear peptide comprising 17 amino acids, which was stable at room temperature and was resistant to degradation by vigorous treatments such as boiling {Gregory and Tracy, 1964; Berson and Yalow, 1971; Yalow and Berson, 1972) and pH extremes (Piszkiewicz, 1974). Such a molecule could thus be studied at room temperature, using conventional biochemical techniques, without the need for any special precautions to preserve its integrity. DA - 1978 DB - OpenUCT DP - University of Cape Town KW - Peptides KW - Physiology KW - Gastrins LK - https://open.uct.ac.za PY - 1978 T1 - Aspects of structure-activity relationships and physiology of gastrin and related peptides TI - Aspects of structure-activity relationships and physiology of gastrin and related peptides UR - http://hdl.handle.net/11427/32048 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/32048
dc.identifier.vancouvercitationNapier BJ. Aspects of structure-activity relationships and physiology of gastrin and related peptides. []. ,Faculty of Health Sciences ,Department of Medicine, 1978 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/32048en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.subjectPeptides
dc.subjectPhysiology
dc.subjectGastrins
dc.titleAspects of structure-activity relationships and physiology of gastrin and related peptides
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
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