The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection

Doctoral Thesis

2011

Permanent link to this Item
http://hdl.handle.net/11427/12245
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thesis_hsf_2011_brombacher_t_m_h_t.pdf (7.19 MB)
Authors
Brombacher, Tiroyaone M H
Supervisors
Brombacher, Frank
Journal Title
Link to Journal
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Volume Title
Publisher
Publisher

University of Cape Town

Department
Division of Immunology
Faculty
Faculty of Health Sciences
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Abstract
Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N. brasiliensis) and Schistosoma mansoni (S. manson!) infection. Among other cell types, IL-4Ra responsive smooth muscle cells influence immunological responses and are needed for host protection during N. brasiliensis and S. mansoni infection.
Description

Includes abstract.


Includes bibliographical references (leaves 101-111).

Keywords
Clinical Laboratory Science and Immunology

Reference:

Brombacher, T. 2011. The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection. University of Cape Town.

Collections
PhD / Doctoral