The first-pass extraction of pindolol in comparison with propranolol in rat liver

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dc.contributor.advisorFolb, Peter Ien_ZA
dc.contributor.authorBasset, Helen Margareten_ZA
dc.date.accessioned2018-03-15T07:38:53Z
dc.date.available2018-03-15T07:38:53Z
dc.date.issued1979en_ZA
dc.description.abstractReports in the literature have shown that in man propranolol has a larger first-pass effect (70%) than pindolol (13%). The aim of this research was to make a direct comparison of first-pass extraction and other pharmacokinetic parameters of these drugs under identical experimental conditions by means of an isolated rat liver perfusion model.en_ZA
dc.identifier.apacitationBasset, H. M. (1979). <i>The first-pass extraction of pindolol in comparison with propranolol in rat liver</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Pharmacology. Retrieved from http://hdl.handle.net/11427/27659en_ZA
dc.identifier.chicagocitationBasset, Helen Margaret. <i>"The first-pass extraction of pindolol in comparison with propranolol in rat liver."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Pharmacology, 1979. http://hdl.handle.net/11427/27659en_ZA
dc.identifier.citationBasset, H. 1979. The first-pass extraction of pindolol in comparison with propranolol in rat liver. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Basset, Helen Margaret AB - Reports in the literature have shown that in man propranolol has a larger first-pass effect (70%) than pindolol (13%). The aim of this research was to make a direct comparison of first-pass extraction and other pharmacokinetic parameters of these drugs under identical experimental conditions by means of an isolated rat liver perfusion model. DA - 1979 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1979 T1 - The first-pass extraction of pindolol in comparison with propranolol in rat liver TI - The first-pass extraction of pindolol in comparison with propranolol in rat liver UR - http://hdl.handle.net/11427/27659 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/27659
dc.identifier.vancouvercitationBasset HM. The first-pass extraction of pindolol in comparison with propranolol in rat liver. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Clinical Pharmacology, 1979 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/27659en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Clinical Pharmacologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPindololen_ZA
dc.subject.otherPropanololen_ZA
dc.subject.otherPerfusionen_ZA
dc.titleThe first-pass extraction of pindolol in comparison with propranolol in rat liveren_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMSc (Med)en_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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