The role of propranolol in the treatment of infantile haemangioma

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dc.contributor.advisorHudson, Donalden_ZA
dc.contributor.authorMoodley, Sean Thirumalayen_ZA
dc.date.accessioned2015-09-15T10:06:09Z
dc.date.available2015-09-15T10:06:09Z
dc.date.issued2013en_ZA
dc.description.abstractThere has been a change in the management of infantile haemangioma with the introduction of propranolol. The aim of this study is to retrospectively evaluate a simple treatment for infantile haemangioma at the Red Cross War Memorial Children’s Hospital (RCWMCH) and document the results. While it is known that all haemangiomas undergo involution at some stage, some haemangiomas pose certain problems. These relate mainly to visual axis obstruction and aesthetics. Subjects are children in the first two years of life presenting with haemangiomas. All patients were treated with oral propranolol in conjunction with haemangioma size documentation, using a simple radiological modality, i.e. ultrasound imaging. Patients are followed up and clinical and radiological evaluations are undertaken to observe changes in size and appearance. Propranolol is non-selective β-adrenergic antagonist that is used extensively for the treatment of a multitude of disorders, mainly cardiovascular indications. The main adverse effects include bradycardia, hypotension and bronchospasms. For the purposes of this study, all subjects were routinely examined, especially with regard to the cardiopulmonary systems. Any perceived anomaly was referred to the cardiorespiratory physicians at RCWMCH for further evaluation, which includes all the necessary investigations such as electrocardiograms(ECG) and echocardiograms. Therefore, only fit healthy patients were selected for this study. Patients are educated and fully informed regarding the adverse effect profile of propranolol, and advised of the appropriate route of management.en_ZA
dc.identifier.apacitationMoodley, S. T. (2013). <i>The role of propranolol in the treatment of infantile haemangioma</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Plastic and Reconstructive Surgery. Retrieved from http://hdl.handle.net/11427/13923en_ZA
dc.identifier.chicagocitationMoodley, Sean Thirumalay. <i>"The role of propranolol in the treatment of infantile haemangioma."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Plastic and Reconstructive Surgery, 2013. http://hdl.handle.net/11427/13923en_ZA
dc.identifier.citationMoodley, S. 2013. The role of propranolol in the treatment of infantile haemangioma. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Moodley, Sean Thirumalay AB - There has been a change in the management of infantile haemangioma with the introduction of propranolol. The aim of this study is to retrospectively evaluate a simple treatment for infantile haemangioma at the Red Cross War Memorial Children’s Hospital (RCWMCH) and document the results. While it is known that all haemangiomas undergo involution at some stage, some haemangiomas pose certain problems. These relate mainly to visual axis obstruction and aesthetics. Subjects are children in the first two years of life presenting with haemangiomas. All patients were treated with oral propranolol in conjunction with haemangioma size documentation, using a simple radiological modality, i.e. ultrasound imaging. Patients are followed up and clinical and radiological evaluations are undertaken to observe changes in size and appearance. Propranolol is non-selective β-adrenergic antagonist that is used extensively for the treatment of a multitude of disorders, mainly cardiovascular indications. The main adverse effects include bradycardia, hypotension and bronchospasms. For the purposes of this study, all subjects were routinely examined, especially with regard to the cardiopulmonary systems. Any perceived anomaly was referred to the cardiorespiratory physicians at RCWMCH for further evaluation, which includes all the necessary investigations such as electrocardiograms(ECG) and echocardiograms. Therefore, only fit healthy patients were selected for this study. Patients are educated and fully informed regarding the adverse effect profile of propranolol, and advised of the appropriate route of management. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - The role of propranolol in the treatment of infantile haemangioma TI - The role of propranolol in the treatment of infantile haemangioma UR - http://hdl.handle.net/11427/13923 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/13923
dc.identifier.vancouvercitationMoodley ST. The role of propranolol in the treatment of infantile haemangioma. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Plastic and Reconstructive Surgery, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/13923en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Plastic and Reconstructive Surgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPlastic and Reconstructive Surgeryen_ZA
dc.titleThe role of propranolol in the treatment of infantile haemangiomaen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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