A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae

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dc.contributor.authorCoert, Claudetteen_ZA
dc.date.accessioned2014-07-30T17:36:15Z
dc.date.available2014-07-30T17:36:15Z
dc.date.issued2002en_ZA
dc.descriptionBibliography: leaves 90-111.
dc.description.abstractIt is well established that histone H1 is involved in facilitating the higher-order structures of chromatin. It has not become possible to test the biochemical function of H1 in Saccharomyces cerevisiae, since the identification of a H1 homologue (Landsman, 1996) with properties of a bona fide linker histone (Patterton et al., 1998; Ali, 2000). Such studies were difficult since no phenotype for a HHO1 deleted strain has been published. In this study I have investigated the response of an HHO1 disrupted strain to numerous conditions including UV radiation, osmotic and oxidative stress, y-irradiation and longevity.en_ZA
dc.identifier.apacitationCoert, C. (2002). <i>A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology. Retrieved from http://hdl.handle.net/11427/4250en_ZA
dc.identifier.chicagocitationCoert, Claudette. <i>"A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2002. http://hdl.handle.net/11427/4250en_ZA
dc.identifier.citationCoert, C. 2002. A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Coert, Claudette AB - It is well established that histone H1 is involved in facilitating the higher-order structures of chromatin. It has not become possible to test the biochemical function of H1 in Saccharomyces cerevisiae, since the identification of a H1 homologue (Landsman, 1996) with properties of a bona fide linker histone (Patterton et al., 1998; Ali, 2000). Such studies were difficult since no phenotype for a HHO1 deleted strain has been published. In this study I have investigated the response of an HHO1 disrupted strain to numerous conditions including UV radiation, osmotic and oxidative stress, y-irradiation and longevity. DA - 2002 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2002 T1 - A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae TI - A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae UR - http://hdl.handle.net/11427/4250 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/4250
dc.identifier.vancouvercitationCoert C. A role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiae. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Molecular and Cell Biology, 2002 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/4250en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Molecular and Cell Biologyen_ZA
dc.publisher.facultyFaculty of Scienceen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherCell Biologyen_ZA
dc.titleA role for Hho1p, a histone H1 homologue, in Saccharomyces cerevisiaeen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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