Small molecule inhibitors of parasitic enzymes

Doctoral Thesis

2005

Permanent link to this Item
http://hdl.handle.net/11427/6298
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thesis_sci_2005_chipeleme_a.pdf (8.97 MB)
Authors
Chipeleme, Alex
Supervisors
Chibale, Kelly
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Publisher
Publisher

University of Cape Town

Department
Department of Chemistry
Faculty
Faculty of Science
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Abstract
The work presented in this thesis is threefold:-(i) development of potential novel inhibitors of cysteine proteases from the causative agents of Malaria, African sleeping sickness and Chagas disease, (ii) development of potential new and novel anti-trypanosomal inhibitors of trypanosome alternative oxidase, and (ii) synthetic and methodological studies.
Description

Includes bibliographical references (leaves 198-213)

Keywords
Chemistry

Reference:

Chipeleme, A. 2005. Small molecule inhibitors of parasitic enzymes. University of Cape Town.

Collections
PhD / Doctoral