Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients

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dc.contributor.authorSimpson, Julie Aen_ZA
dc.contributor.authorAgbenyega, Tsirien_ZA
dc.contributor.authorBarnes, Karen Ien_ZA
dc.contributor.authorPerri, Gianni Dien_ZA
dc.contributor.authorFolb, Peteren_ZA
dc.contributor.authorGomes, Melbaen_ZA
dc.contributor.authorKrishna, Sanjeeven_ZA
dc.contributor.authorKrudsood, Srivichaen_ZA
dc.contributor.authorLooareesuwan, Sornchaien_ZA
dc.contributor.authorMansor, Sharifen_ZA
dc.date.accessioned2015-11-23T12:36:26Z
dc.date.available2015-11-23T12:36:26Z
dc.date.issued2006en_ZA
dc.description.abstractA study of the population pharmacokinetics of intra-rectal artesunate in patients with moderately severe falciparum malaria found the pharmacokinetic properties of dihydroartemisinin were affected only by gender and body weight.en_ZA
dc.identifier.apacitationSimpson, J. A., Agbenyega, T., Barnes, K. I., Perri, G. D., Folb, P., Gomes, M., ... Mansor, S. (2006). Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients. <i>PLOS Medicince</i>, http://hdl.handle.net/11427/15337en_ZA
dc.identifier.chicagocitationSimpson, Julie A, Tsiri Agbenyega, Karen I Barnes, Gianni Di Perri, Peter Folb, Melba Gomes, Sanjeev Krishna, Srivicha Krudsood, Sornchai Looareesuwan, and Sharif Mansor "Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients." <i>PLOS Medicince</i> (2006) http://hdl.handle.net/11427/15337en_ZA
dc.identifier.citationSimpson, J. A., Agbenyega, T., Barnes, K. I., Di Perri, G., Folb, P., Gomes, M., ... & White, N. J. (2006). Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients. PLoS Med, 3(11), e444. doi:10.1371/journal.pmed.0030444en_ZA
dc.identifier.ris TY - Journal Article AU - Simpson, Julie A AU - Agbenyega, Tsiri AU - Barnes, Karen I AU - Perri, Gianni Di AU - Folb, Peter AU - Gomes, Melba AU - Krishna, Sanjeev AU - Krudsood, Srivicha AU - Looareesuwan, Sornchai AU - Mansor, Sharif AB - A study of the population pharmacokinetics of intra-rectal artesunate in patients with moderately severe falciparum malaria found the pharmacokinetic properties of dihydroartemisinin were affected only by gender and body weight. DA - 2006 DB - OpenUCT DO - 10.1371/journal.pmed.0030444 DP - University of Cape Town J1 - PLOS Medicince LK - https://open.uct.ac.za PB - University of Cape Town PY - 2006 T1 - Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients TI - Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients UR - http://hdl.handle.net/11427/15337 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15337
dc.identifier.urihttp://dx.doi.org/10.1371/journal.pmed.0030444
dc.identifier.vancouvercitationSimpson JA, Agbenyega T, Barnes KI, Perri GD, Folb P, Gomes M, et al. Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients. PLOS Medicince. 2006; http://hdl.handle.net/11427/15337.en_ZA
dc.language.isoengen_ZA
dc.publisherPublic Library of Scienceen_ZA
dc.publisher.departmentDivision of Clinical Pharmacologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_ZA
dc.rights.holder© 2006 Simpson et alen_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/4.0en_ZA
dc.sourcePLOS Medicinceen_ZA
dc.source.urihttp://journals.plos.org/plosmedicineen_ZA
dc.subject.otherPharmacokineticsen_ZA
dc.subject.otherMalariaen_ZA
dc.subject.otherMalarial parasitesen_ZA
dc.subject.otherDrug therapyen_ZA
dc.subject.otherAntimalarialsen_ZA
dc.subject.otherDrug absorptionen_ZA
dc.subject.otherBody weighten_ZA
dc.subject.otherPharmacokinetic analysisen_ZA
dc.titlePopulation pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patientsen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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