Studies on growth, modelling and pigment production by the yeast Phaffia rhodozyma during fed-batch cultivation
Journal Article
1996
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Biotechnology Letters
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Springer
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University of Cape Town
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Abstract
As Phaffia rhodozyma is a Crabtree positive yeast, its cell yield and pigment production are
reduced at high sugar concentrations. A method for maintaining low growth medium sugar
concentrations is fed-batch culture. Using a mass balance approach and Monod growth kinetics a
model is presented which describes the fed-batch culture of Phaffia rhodozyma and enables the
calculation of a feed regime to obtain the maximum yield of cells and pigment. Although developed
on a glucose medium, the model was also applied successfully to a molasses-based medium.
Description
Reference:
Reynders, M. B., Rawlings, D. E., & Harrison, S. T. L. (1996). Studies on the growth, modelling and pigment production by the yeast Phaffia rhodozyma during fed-batch cultivation. Biotechnology letters, 18(6), 649-654.