On the humoral mediation of the intestinal phase of gastric secretion

dc.contributor.authorKester, Ralph Charles
dc.date.accessioned2020-06-04T08:17:19Z
dc.date.available2020-06-04T08:17:19Z
dc.date.issued1973
dc.date.updated2020-04-07T10:31:52Z
dc.description.abstractThe existence of a stimulatory intestinal phase of gastric acid secretion has been suspected for some time, and recently the importance of this phase has been recognized. The intestinal phase is of particular interest in relation to the profound gastric hypersecretion associated with portacaval anastomosis. The results of many studies in dogs, and recently in man, have demonstrated conclusively that shunt-related gastric hyper-secretion is due to unmasking of the intestinal phase by hepatic bypass of a humoral stimulant that is normally inactivated by the liver. Definitive experiments have shown that this humoral agent is a hormone that arises in the jejunum. Elaboration of the hormone is triggered both by the entry of food into the jejunum and by a brief period of jejunal distension with a balloon.
dc.identifier.apacitationKester, R. C. (1973). <i>On the humoral mediation of the intestinal phase of gastric secretion</i>. (). ,Faculty of Health Sciences ,Department of Medicine. Retrieved from en_ZA
dc.identifier.chicagocitationKester, Ralph Charles. <i>"On the humoral mediation of the intestinal phase of gastric secretion."</i> ., ,Faculty of Health Sciences ,Department of Medicine, 1973. en_ZA
dc.identifier.citationKester, R.C. 1973. On the humoral mediation of the intestinal phase of gastric secretion. . ,Faculty of Health Sciences ,Department of Medicine. en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Kester, Ralph Charles AB - The existence of a stimulatory intestinal phase of gastric acid secretion has been suspected for some time, and recently the importance of this phase has been recognized. The intestinal phase is of particular interest in relation to the profound gastric hypersecretion associated with portacaval anastomosis. The results of many studies in dogs, and recently in man, have demonstrated conclusively that shunt-related gastric hyper-secretion is due to unmasking of the intestinal phase by hepatic bypass of a humoral stimulant that is normally inactivated by the liver. Definitive experiments have shown that this humoral agent is a hormone that arises in the jejunum. Elaboration of the hormone is triggered both by the entry of food into the jejunum and by a brief period of jejunal distension with a balloon. DA - 1973 DB - OpenUCT DP - University of Cape Town KW - Gastrointestinal Hormones LK - https://open.uct.ac.za PY - 1973 T1 - On the humoral mediation of the intestinal phase of gastric secretion TI - On the humoral mediation of the intestinal phase of gastric secretion UR - ER - en_ZA
dc.identifier.urihttps://hdl.handle.net/11427/32033
dc.identifier.vancouvercitationKester RC. On the humoral mediation of the intestinal phase of gastric secretion. []. ,Faculty of Health Sciences ,Department of Medicine, 1973 [cited yyyy month dd]. Available from: en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.subjectGastrointestinal Hormones
dc.titleOn the humoral mediation of the intestinal phase of gastric secretion
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
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