The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro

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dc.contributor.advisorFolb, Peter Ien_ZA
dc.contributor.advisorSmith, Peter Jen_ZA
dc.contributor.advisorCampbell, William Een_ZA
dc.contributor.authorMatsabisa, Motlalepula Gilberten_ZA
dc.date.accessioned2014-07-29T09:07:18Z
dc.date.available2014-07-29T09:07:18Z
dc.date.issued2001en_ZA
dc.descriptionIncludes bibliographical references.
dc.description.abstractTwo plants, Dicoma anomala [Sond.]; a member of the Asteraceae and Sclerocarya birrea [(A. Rich) Hoechst. subspecies caffra (Sond.) Kokwaro], a member of the Anarcadiaceae families, are used widely in Africa for a variety of traditional treatments. In this thesis it has been shown that these plants possess in vitro pharmacological activities against the malaria parasite. The extracts of D. anomala are active in vitro against Plasmodium falciparum and those of S. birrea selectively enhance the in vitro accumulation of chloroquine in resistant strains of Plasmodium falciparum.en_ZA
dc.identifier.apacitationMatsabisa, M. G. (2001). <i>The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/3427en_ZA
dc.identifier.chicagocitationMatsabisa, Motlalepula Gilbert. <i>"The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2001. http://hdl.handle.net/11427/3427en_ZA
dc.identifier.citationMatsabisa, M. 2001. The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Matsabisa, Motlalepula Gilbert AB - Two plants, Dicoma anomala [Sond.]; a member of the Asteraceae and Sclerocarya birrea [(A. Rich) Hoechst. subspecies caffra (Sond.) Kokwaro], a member of the Anarcadiaceae families, are used widely in Africa for a variety of traditional treatments. In this thesis it has been shown that these plants possess in vitro pharmacological activities against the malaria parasite. The extracts of D. anomala are active in vitro against Plasmodium falciparum and those of S. birrea selectively enhance the in vitro accumulation of chloroquine in resistant strains of Plasmodium falciparum. DA - 2001 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2001 T1 - The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro TI - The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro UR - http://hdl.handle.net/11427/3427 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3427
dc.identifier.vancouvercitationMatsabisa MG. The antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitro. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2001 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3427en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedicineen_ZA
dc.titleThe antimalarial activity of Dicoma anomala and the chloroquine resistance reversing effects of Sclerocarya birrea on Plasmodium falciparum in vitroen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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