The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine design

Simple item page
dc.contributor.authorZembe, Len_ZA
dc.contributor.authorTongo, Men_ZA
dc.contributor.authorEbong, Een_ZA
dc.contributor.authorNgobe, EMen_ZA
dc.contributor.authorWilliamson, Cen_ZA
dc.contributor.authorBurgers, Wen_ZA
dc.date.accessioned2015-11-23T11:37:04Z
dc.date.available2015-11-23T11:37:04Z
dc.date.issued2012en_ZA
dc.description.abstractThe high level of genetic diversity of HIV-1 poses a major challenge for global vaccine development. Vaccines based on centralized sequences would minimize genetic distances to multiple clades and potentially maximize cross-reactivity. Whether reactivity of these centralized peptide reagents differs in mono- and multi-clade epidemic is unknown.en_ZA
dc.identifier.apacitationZembe, L., Tongo, M., Ebong, E., Ngobe, E., Williamson, C., & Burgers, W. (2012). The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine design. <i>Retrovirology</i>, http://hdl.handle.net/11427/15217en_ZA
dc.identifier.chicagocitationZembe, L, M Tongo, E Ebong, EM Ngobe, C Williamson, and W Burgers "The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine design." <i>Retrovirology</i> (2012) http://hdl.handle.net/11427/15217en_ZA
dc.identifier.citationZembe, L., Tongo, M., Ebong, E., Ngobe, E. M., Williamson, C., & Burgers, W. (2012). The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono-and multi-clade epidemics: implications for HIV vaccine design. Retrovirology, 9(Suppl 2), P253.en_ZA
dc.identifier.ris TY - Journal Article AU - Zembe, L AU - Tongo, M AU - Ebong, E AU - Ngobe, EM AU - Williamson, C AU - Burgers, W AB - The high level of genetic diversity of HIV-1 poses a major challenge for global vaccine development. Vaccines based on centralized sequences would minimize genetic distances to multiple clades and potentially maximize cross-reactivity. Whether reactivity of these centralized peptide reagents differs in mono- and multi-clade epidemic is unknown. DA - 2012 DB - OpenUCT DO - 10.1186/1742-4690-9-S2-P253 DP - University of Cape Town J1 - Retrovirology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine design TI - The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine design UR - http://hdl.handle.net/11427/15217 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15217
dc.identifier.urihttp://dx.doi.org/10.1186/1742-4690-9-S2-P253
dc.identifier.vancouvercitationZembe L, Tongo M, Ebong E, Ngobe E, Williamson C, Burgers W. The recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine design. Retrovirology. 2012; http://hdl.handle.net/11427/15217.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDivision of Medical Microbiologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2012 Zembe et al; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceRetrovirologyen_ZA
dc.source.urihttp://www.retrovirology.com/en_ZA
dc.subject.otherHIV-1en_ZA
dc.subject.otherglobal vaccine developmenten_ZA
dc.titleThe recognition of HIV-1 consensus group M Gag and Nef peptide reagents in mono- and multi-clade epidemics: implications for HIV vaccine designen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Zembe_recognition_of_HIV_1_consensus_2012.pdf
Size:
128.5 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Journal Articles