An in vitro study of neutrophil chemotaxis

dc.contributor.advisorDowdle, E B
dc.contributor.authorTodd, Gail
dc.date.accessioned2020-05-20T09:50:43Z
dc.date.available2020-05-20T09:50:43Z
dc.date.issued1976
dc.date.updated2020-04-14T11:20:22Z
dc.description.abstractWhen, at the beginning of 1972, my scientific attention was first drawn to the subject of cellular participation in the inflanunatory response, I was struck by the need for an understanding of the cellular and molecular mechanisms whereby blood leucocytes are attracted to an area of injury. The literature at that time contained good technical accounts of methods available for studying chemotaxis in vitro and many reports of diverse compounds of biological origin with attractant, or chemotactic, properties for motile, phagocytic cells. In general, these reports tended to substantiate the belief that chemical substances generated at an inflannnatory source attracted cells to that source in a teleologically appropriate way and they justified, by the consistent correlation observed, the relevance of in vitro procedures for studying the phenomenon. In other words, answers were available to the question "What substances attract?"; very few were available to the question, "How do they attract?".
dc.identifier.apacitationTodd, G. (1976). <i>An in vitro study of neutrophil chemotaxis</i>. (). ,Faculty of Health Sciences ,Department of Human Biology. Retrieved from en_ZA
dc.identifier.chicagocitationTodd, Gail. <i>"An in vitro study of neutrophil chemotaxis."</i> ., ,Faculty of Health Sciences ,Department of Human Biology, 1976. en_ZA
dc.identifier.citationTodd, G. 1976. An in vitro study of neutrophil chemotaxis. . ,Faculty of Health Sciences ,Department of Human Biology. en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Todd, Gail AB - When, at the beginning of 1972, my scientific attention was first drawn to the subject of cellular participation in the inflanunatory response, I was struck by the need for an understanding of the cellular and molecular mechanisms whereby blood leucocytes are attracted to an area of injury. The literature at that time contained good technical accounts of methods available for studying chemotaxis in vitro and many reports of diverse compounds of biological origin with attractant, or chemotactic, properties for motile, phagocytic cells. In general, these reports tended to substantiate the belief that chemical substances generated at an inflannnatory source attracted cells to that source in a teleologically appropriate way and they justified, by the consistent correlation observed, the relevance of in vitro procedures for studying the phenomenon. In other words, answers were available to the question "What substances attract?"; very few were available to the question, "How do they attract?". DA - 1976 DB - OpenUCT DP - University of Cape Town KW - Neutrophils KW - chemotaxis KW - leucocytes LK - https://open.uct.ac.za PY - 1976 T1 - An in vitro study of neutrophil chemotaxis TI - An in vitro study of neutrophil chemotaxis UR - ER - en_ZA
dc.identifier.urihttps://hdl.handle.net/11427/31946
dc.identifier.vancouvercitationTodd G. An in vitro study of neutrophil chemotaxis. []. ,Faculty of Health Sciences ,Department of Human Biology, 1976 [cited yyyy month dd]. Available from: en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Human Biology
dc.publisher.facultyFaculty of Health Sciences
dc.subjectNeutrophils
dc.subjectchemotaxis
dc.subjectleucocytes
dc.titleAn in vitro study of neutrophil chemotaxis
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
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