An investigation into the development of plant-derived vaccines against human papillomavirus type 11 and Cottontail rabbit papillomavirus

Doctoral Thesis

2004

Permanent link to this Item
http://hdl.handle.net/11427/7433
Files
thesis_sci_2004_kohl_to (1).pdf (35.58 MB)
Authors
Kohl, Thomas Oliver
Supervisors
Rybicki, Ed
Becker-Hitzeroth, Inga I
Journal Title
Link to Journal
Journal ISSN
Volume Title
Publisher
Publisher

University of Cape Town

Department
Department of Molecular and Cell Biology
Faculty
Faculty of Science
License
Series
Abstract
The principal object of this thesis was to investigate the feasibility of developing a novel plant-derived vaccine against Human papillomavirus type 11 (HPV -11), the causal agent of genital warts and laryngeal condylomas. A secondary objective was a proof-of-concept study using Cottontail rabbit papillomavirus (CRPV), as this is a viable animal model for human papillomavirus vaccines. Accordingly, I investigated and compared the potential of two different plant expression systems.
Description

Includes bibliographical references (leaves 207-241).

Keywords
Cell Biology

Reference:

Kohl, T. 2004. An investigation into the development of plant-derived vaccines against human papillomavirus type 11 and Cottontail rabbit papillomavirus. University of Cape Town.

Collections
PhD / Doctoral