One Health-One City; the extent of Shiga-toxin producing Escherichia coli in Cape Town

Doctoral Thesis

2017

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http://hdl.handle.net/11427/26938
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thesis_hsf_2017_kalule_john_bosco.pdf (5.96 MB)
Authors
Kalule, John Bosco
Supervisors
Nicol, Mark P
Keddy, Karen H
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University of Cape Town

Department
Division of Medical Microbiology
Faculty
Faculty of Health Sciences
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Abstract
The estimated global burden of STEC (Shiga toxin producing Escherichia coli) is 2,481,511 illnesses, 269 deaths, and 26,827 DALYs with 48% of these being foodborne. This thesis provides information on STEC diagnostic strategy, undetected STEC in a tertiary referral hospital in Cape Town, and the virulence and antimicrobial resistance properties of tellurite resistant diarrheic E. coli isolated on CHROMagar(TM)STEC (CHROMagar Microbiology, Paris, France). Deploying the One - Health surveillance approach to study selected diarrheic bacterial pathogens in an informal settlement setting, this study sheds light on the extent of bacterial foodborne pathogens in human and non-human sources.
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Keywords
Medical Microbiology

Reference:

Kalule, J. 2017. One Health-One City; the extent of Shiga-toxin producing Escherichia coli in Cape Town. University of Cape Town.

Collections
PhD / Doctoral