P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism
Doctoral Thesis
2010
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University of Cape Town
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Abstract
This thesis describes the development of a novel cytochrome P450 array format, the P450 Biochip that allows quantitative and truly high-throughput measurement of cytochrome P450-mediated turnover reactions in sub-nanolitre volumes.
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Includes bibliographical references (leaves 224-243).
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Reference:
Beeton-Kempen, N. 2010. P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism. University of Cape Town.