Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa

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dc.contributor.advisorParker, M Iqbalen_ZA
dc.contributor.advisorMathew, Chrisen_ZA
dc.contributor.authorMatejcic, Marcoen_ZA
dc.date.accessioned2014-07-28T14:55:42Z
dc.date.available2014-07-28T14:55:42Z
dc.date.issued2013en_ZA
dc.descriptionIncludes abstract.
dc.descriptionIncludes bibliographical references.
dc.description.abstractOesophageal squamous cell carcinoma (OSCC) is a complex disease, determined by the interaction of genetic factors with environmental risk factors. In South Africa, OSCC is a major malignancy occurring with high incidence in the Black and Mixed Ancestry populations. Previous studies by our research group have reported that genetic polymorphism of xenobiotic metabolizing enzymes influence greatly the detoxification of tobacco-related carcinogens in vivo, and may therefore have an important role in determining susceptibility to oesophageal cancer.en_ZA
dc.identifier.apacitationMatejcic, M. (2013). <i>Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry. Retrieved from http://hdl.handle.net/11427/3139en_ZA
dc.identifier.chicagocitationMatejcic, Marco. <i>"Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2013. http://hdl.handle.net/11427/3139en_ZA
dc.identifier.citationMatejcic, M. 2013. Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Matejcic, Marco AB - Oesophageal squamous cell carcinoma (OSCC) is a complex disease, determined by the interaction of genetic factors with environmental risk factors. In South Africa, OSCC is a major malignancy occurring with high incidence in the Black and Mixed Ancestry populations. Previous studies by our research group have reported that genetic polymorphism of xenobiotic metabolizing enzymes influence greatly the detoxification of tobacco-related carcinogens in vivo, and may therefore have an important role in determining susceptibility to oesophageal cancer. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa TI - Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa UR - http://hdl.handle.net/11427/3139 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3139
dc.identifier.vancouvercitationMatejcic M. Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3139en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Medical Biochemistryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedical Biochemistryen_ZA
dc.titleIdentification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africaen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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