Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis

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dc.contributor.advisorNoakes, Timothy Den_ZA
dc.contributor.authorDiesel, Wayne Jonathanen_ZA
dc.date.accessioned2017-12-11T14:14:28Z
dc.date.available2017-12-11T14:14:28Z
dc.date.issued1994en_ZA
dc.description.abstractExercise tolerance, measured as peak oxygen consumption (VO₂ peak), is very low in patients with end-stage renal failure undergoing maintenance haemodialysis. Due to their associated anaemia and low peak heart rates during maximal exercise it has been argued that the reduced blood oxygen carrying capacity and central cardiovascular limitations are primarily responsible for the poor exercise tolerance of these patients. However, others suggest that peripheral (skeletal muscle) limitations including impaired substrate utilization, muscle weakness caused by peripheral neuropathy and myopathy, malnutrition and general physical deconditioning are responsible for the poor exercise tolerance. The present thesis was therefore designed to study whether central cardiovascular function or anaemia or muscle weakness causes patients with end-stage renal failure to terminate exercise at workrates well below those achieved by healthy controls.en_ZA
dc.identifier.apacitationDiesel, W. J. (1994). <i>Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,MRC/UCT RU for Exercise and Sport Medicine. Retrieved from http://hdl.handle.net/11427/26548en_ZA
dc.identifier.chicagocitationDiesel, Wayne Jonathan. <i>"Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,MRC/UCT RU for Exercise and Sport Medicine, 1994. http://hdl.handle.net/11427/26548en_ZA
dc.identifier.citationDiesel, W. 1994. Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Diesel, Wayne Jonathan AB - Exercise tolerance, measured as peak oxygen consumption (VO₂ peak), is very low in patients with end-stage renal failure undergoing maintenance haemodialysis. Due to their associated anaemia and low peak heart rates during maximal exercise it has been argued that the reduced blood oxygen carrying capacity and central cardiovascular limitations are primarily responsible for the poor exercise tolerance of these patients. However, others suggest that peripheral (skeletal muscle) limitations including impaired substrate utilization, muscle weakness caused by peripheral neuropathy and myopathy, malnutrition and general physical deconditioning are responsible for the poor exercise tolerance. The present thesis was therefore designed to study whether central cardiovascular function or anaemia or muscle weakness causes patients with end-stage renal failure to terminate exercise at workrates well below those achieved by healthy controls. DA - 1994 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1994 T1 - Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis TI - Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis UR - http://hdl.handle.net/11427/26548 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/26548
dc.identifier.vancouvercitationDiesel WJ. Factors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysis. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,MRC/UCT RU for Exercise and Sport Medicine, 1994 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/26548en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentMRC/UCT RU for Exercise and Sport Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherExercise Tolerance - physiologyen_ZA
dc.subject.otherKidney failure, Chronic - Physiopathologyen_ZA
dc.subject.otherHemodialysisen_ZA
dc.subject.otherMedical Physiologyen_ZA
dc.titleFactors limiting the exercise tolerance of patients with end-stage renal failure undergoing maintenance haemodialysisen_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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